Device Exchange in HeartMate II Recipients: Long-Term Outcomes and Risk of Thrombosis Recurrence

Allison P. Levin, Nir Uriel, Hiroo Takayama, Kanika P. Mody, Takeyoshi Ota, Melana Yuzefpolskaya, Paolo C. Colombo, Arthur R. Garan, Marija Dionizovik-Dimanovski, Robert N. Sladen, Yoshifumi Naka, Ulrich P. Jorde

Research output: Contribution to journalArticle

25 Scopus citations

Abstract

Successful long-term use of the HeartMate II (HM II) left ventricular assist device has become commonplace but may be complicated by mechanical failure, infection, or thrombosis necessitating device exchange (DE). A subcostal approach to device exchange with motor exchange only is less traumatic, but long-term outcomes have not been reported. A retrospective chart review of all patients who required HM II to HM II device exchange at our institution was conducted. Of the 232 HM II patients implanted between January 2008 and July 2013, 28 required 36 device exchanges during a follow-up of 33.72 ± 17.25 months. The Kaplan-Meier 1 year survival was 63% for sternotomy exchanges and 100% for subcostal exchanges. Twenty-one exchanges were performed for initial or recurring device thrombosis. Although there was no difference in the risk of subsequent thrombosis after subcostal versus sternotomy exchange, the overall risk of recurring device thrombosis after device exchange for the same was high (31%). HM II device exchange via the subcostal approach has excellent short-and long-term outcomes. Device exchange performed for thrombosis is associated with a high recurrence risk irrespective of surgical approach.

Original languageEnglish (US)
Pages (from-to)144-149
Number of pages6
JournalASAIO Journal
Volume61
Issue number2
DOIs
StatePublished - Jul 21 2015
Externally publishedYes

Keywords

  • CF-LVAD
  • Exchange
  • LVAD
  • Malfunction
  • Sternotomy
  • Subcostal
  • Thrombosis

ASJC Scopus subject areas

  • Biophysics
  • Bioengineering
  • Biomaterials
  • Biomedical Engineering

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  • Cite this

    Levin, A. P., Uriel, N., Takayama, H., Mody, K. P., Ota, T., Yuzefpolskaya, M., Colombo, P. C., Garan, A. R., Dionizovik-Dimanovski, M., Sladen, R. N., Naka, Y., & Jorde, U. P. (2015). Device Exchange in HeartMate II Recipients: Long-Term Outcomes and Risk of Thrombosis Recurrence. ASAIO Journal, 61(2), 144-149. https://doi.org/10.1097/MAT.0000000000000170