Development of a lectin microarray for the rapid analysis of protein glycopatterns

Kanoelani T. Pilobello, Lakshmipriya Krishnamoorthy, Deepika Slawek, Lara K. Mahal

Research output: Contribution to journalArticle

209 Citations (Scopus)

Abstract

Glycosylation plays a role in a wide variety of biological processes including bacterial pathogenesis, tumor cell metastasis and inflammation. Despite the importance of carbohydrates, few techniques exist for the rapid and systematic evaluation of protein glycosylation. This paper describes a lectin microarray for the rapid analysis of protein glycopatterns (see scheme).

Original languageEnglish (US)
Pages (from-to)985-989
Number of pages5
JournalChemBioChem
Volume6
Issue number6
DOIs
StatePublished - Jun 1 2005
Externally publishedYes

Fingerprint

Glycosylation
Protein Array Analysis
Microarrays
Lectins
Biological Phenomena
Tumors
Proteins
Cells
Carbohydrates
Neoplasm Metastasis
Inflammation
Neoplasms

Keywords

  • Analytical methods
  • Carbohydrates
  • Glycomics
  • Lectin
  • Microarrays

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Medicine
  • Molecular Biology
  • Organic Chemistry

Cite this

Development of a lectin microarray for the rapid analysis of protein glycopatterns. / Pilobello, Kanoelani T.; Krishnamoorthy, Lakshmipriya; Slawek, Deepika; Mahal, Lara K.

In: ChemBioChem, Vol. 6, No. 6, 01.06.2005, p. 985-989.

Research output: Contribution to journalArticle

Pilobello, Kanoelani T. ; Krishnamoorthy, Lakshmipriya ; Slawek, Deepika ; Mahal, Lara K. / Development of a lectin microarray for the rapid analysis of protein glycopatterns. In: ChemBioChem. 2005 ; Vol. 6, No. 6. pp. 985-989.
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