Development and maintenance of neuronal architecture at the ventral midline of C. elegans

Oliver Hobert, Hannes E. Buelow

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

Work in flies, nematodes and vertebrates has shown that genes involved in axon patterning at the ventral midline are functionally conserved across phylogeny. Recent studies in Caenorhabditis elegans have implicated several new extracellular molecules, such as nidogen and heparan sulfate proteoglycans, in axonal tract formation at the midline. Furthermore, a conceptually new mechanism that regulates the maintenance of axon positioning at the midline has been described in C. elegans.

Original languageEnglish (US)
Pages (from-to)70-78
Number of pages9
JournalCurrent Opinion in Neurobiology
Volume13
Issue number1
DOIs
StatePublished - Feb 2003
Externally publishedYes

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Caenorhabditis elegans
Axons
Maintenance
Heparan Sulfate Proteoglycans
Phylogeny
Diptera
Vertebrates
Genes
nidogen

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Development and maintenance of neuronal architecture at the ventral midline of C. elegans. / Hobert, Oliver; Buelow, Hannes E.

In: Current Opinion in Neurobiology, Vol. 13, No. 1, 02.2003, p. 70-78.

Research output: Contribution to journalArticle

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