TY - JOUR
T1 - Development and maintenance of neuronal architecture at the ventral midline of C. elegans
AU - Hobert, Oliver
AU - Bülow, Hannes
PY - 2003/2
Y1 - 2003/2
N2 - Work in flies, nematodes and vertebrates has shown that genes involved in axon patterning at the ventral midline are functionally conserved across phylogeny. Recent studies in Caenorhabditis elegans have implicated several new extracellular molecules, such as nidogen and heparan sulfate proteoglycans, in axonal tract formation at the midline. Furthermore, a conceptually new mechanism that regulates the maintenance of axon positioning at the midline has been described in C. elegans.
AB - Work in flies, nematodes and vertebrates has shown that genes involved in axon patterning at the ventral midline are functionally conserved across phylogeny. Recent studies in Caenorhabditis elegans have implicated several new extracellular molecules, such as nidogen and heparan sulfate proteoglycans, in axonal tract formation at the midline. Furthermore, a conceptually new mechanism that regulates the maintenance of axon positioning at the midline has been described in C. elegans.
UR - http://www.scopus.com/inward/record.url?scp=0037321080&partnerID=8YFLogxK
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U2 - 10.1016/S0959-4388(03)00002-3
DO - 10.1016/S0959-4388(03)00002-3
M3 - Review article
C2 - 12593984
AN - SCOPUS:0037321080
SN - 0959-4388
VL - 13
SP - 70
EP - 78
JO - Current Opinion in Neurobiology
JF - Current Opinion in Neurobiology
IS - 1
ER -