Determinants of mRNA localization

Edward H. Kislauskis, Robert H. Singer

Research output: Contribution to journalArticle

102 Citations (Scopus)

Abstract

RNA localization provides a mechanism for protein targeting within developing or differentiating cells. Specific cis-acting sequences on mRNA mediate this process. Such 'localizer' or 'zipcode' nucleic acid sequences have been restricted to the 3′ untranslated region of several mRNAs. The presence of genetic information denoting a spatial component of translation adds a new dimension to gene expression.

Original languageEnglish (US)
Pages (from-to)975-978
Number of pages4
JournalCurrent Opinion in Cell Biology
Volume4
Issue number6
DOIs
StatePublished - 1992
Externally publishedYes

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Messenger RNA
3' Untranslated Regions
Protein Transport
Nucleic Acids
RNA
Gene Expression

ASJC Scopus subject areas

  • Cell Biology

Cite this

Determinants of mRNA localization. / Kislauskis, Edward H.; Singer, Robert H.

In: Current Opinion in Cell Biology, Vol. 4, No. 6, 1992, p. 975-978.

Research output: Contribution to journalArticle

Kislauskis, Edward H. ; Singer, Robert H. / Determinants of mRNA localization. In: Current Opinion in Cell Biology. 1992 ; Vol. 4, No. 6. pp. 975-978.
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