Determinants of mRNA localization

Edward H. Kislauskis; Robert H. Singer

doi:10.1016/0955-0674(92)90128-Y

Determinants of mRNA localization

Edward H. Kislauskis, Robert H. Singer

Research output: Contribution to journal › Article › peer-review

117 Scopus citations

Abstract

RNA localization provides a mechanism for protein targeting within developing or differentiating cells. Specific cis-acting sequences on mRNA mediate this process. Such 'localizer' or 'zipcode' nucleic acid sequences have been restricted to the 3′ untranslated region of several mRNAs. The presence of genetic information denoting a spatial component of translation adds a new dimension to gene expression.

Original language	English (US)
Pages (from-to)	975-978
Number of pages	4
Journal	Current Opinion in Cell Biology
Volume	4
Issue number	6
DOIs	https://doi.org/10.1016/0955-0674(92)90128-Y
State	Published - Dec 1992
Externally published	Yes

ASJC Scopus subject areas

Cell Biology

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10.1016/0955-0674(92)90128-Y

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title = "Determinants of mRNA localization",

abstract = "RNA localization provides a mechanism for protein targeting within developing or differentiating cells. Specific cis-acting sequences on mRNA mediate this process. Such 'localizer' or 'zipcode' nucleic acid sequences have been restricted to the 3′ untranslated region of several mRNAs. The presence of genetic information denoting a spatial component of translation adds a new dimension to gene expression.",

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year = "1992",

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AB - RNA localization provides a mechanism for protein targeting within developing or differentiating cells. Specific cis-acting sequences on mRNA mediate this process. Such 'localizer' or 'zipcode' nucleic acid sequences have been restricted to the 3′ untranslated region of several mRNAs. The presence of genetic information denoting a spatial component of translation adds a new dimension to gene expression.

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Determinants of mRNA localization

Abstract

ASJC Scopus subject areas

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