Detection of human papillomavirus deoxyribonucleic acid from vulvar dystrophies and vulvar intraepithelial neoplastic lesions

Mickey Karram, Bannie Tabor, David Smotkin, Felix Wettstein, Narender Bhatia, John Micha

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

Vulvar biopsy specimens from 16 patients with gross lesions of the vulva consistent with vulvar dystrophy were examined histologically and for the presence of human papillomavirus deoxyribonucleic acid by southern blot hybridization. None of the nonatypical dystrophies probed positive for human papillomavirus; however, three of five atypical hyperplastic dystrophies (vulvar intraepithelial neoplasia) contained human papillomavirus deoxyribonucleic acid type 16. We conclude that human papillomavirus does not seem to be a causal factor in nonatypical chronic epithelial changes of the vulva.

Original languageEnglish (US)
Pages (from-to)22-23
Number of pages2
JournalAmerican Journal of Obstetrics and Gynecology
Volume159
Issue number1
DOIs
StatePublished - 1988
Externally publishedYes

Fingerprint

Vulva
DNA
Southern Blotting
Biopsy
Neoplasms

Keywords

  • Dystrophy
  • human papillomavirus
  • vulvar intraepithelial neoplasia

ASJC Scopus subject areas

  • Medicine(all)
  • Obstetrics and Gynecology

Cite this

Detection of human papillomavirus deoxyribonucleic acid from vulvar dystrophies and vulvar intraepithelial neoplastic lesions. / Karram, Mickey; Tabor, Bannie; Smotkin, David; Wettstein, Felix; Bhatia, Narender; Micha, John.

In: American Journal of Obstetrics and Gynecology, Vol. 159, No. 1, 1988, p. 22-23.

Research output: Contribution to journalArticle

Karram, Mickey ; Tabor, Bannie ; Smotkin, David ; Wettstein, Felix ; Bhatia, Narender ; Micha, John. / Detection of human papillomavirus deoxyribonucleic acid from vulvar dystrophies and vulvar intraepithelial neoplastic lesions. In: American Journal of Obstetrics and Gynecology. 1988 ; Vol. 159, No. 1. pp. 22-23.
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AU - Bhatia, Narender

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