Abstract
Vulvar biopsy specimens from 16 patients with gross lesions of the vulva consistent with vulvar dystrophy were examined histologically and for the presence of human papillomavirus deoxyribonucleic acid by southern blot hybridization. None of the nonatypical dystrophies probed positive for human papillomavirus; however, three of five atypical hyperplastic dystrophies (vulvar intraepithelial neoplasia) contained human papillomavirus deoxyribonucleic acid type 16. We conclude that human papillomavirus does not seem to be a causal factor in nonatypical chronic epithelial changes of the vulva.
Original language | English (US) |
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Pages (from-to) | 22-23 |
Number of pages | 2 |
Journal | American journal of obstetrics and gynecology |
Volume | 159 |
Issue number | 1 |
DOIs | |
State | Published - Jul 1988 |
Externally published | Yes |
Keywords
- Dystrophy
- human papillomavirus
- vulvar intraepithelial neoplasia
ASJC Scopus subject areas
- Obstetrics and Gynecology