Detection of adenocarcinoma by urinary microsatellite analysis after augmentation cystoplasty.

S. G. Docimo, N. H. Chow, G. Steiner, R. I. Silver, R. Rodriguez, S. Kinsman, D. Sidransky, M. Schoenberg

Research output: Contribution to journalArticle

9 Scopus citations

Abstract

Augmentation cystoplasty is associated with an increased risk of bladder cancer development between 10 and 20 years after augmentation. Using microsatellite analysis, we analyzed urine obtained before surgical resection of the malignant lesion from a patient who developed invasive adenocarcinoma after augmentation cystoplasty. Loss of heterozygosity was identified in both urine and tumor samples from this patient. This observation suggests that microsatellite urine analysis may be useful as a monitoring tool for patients after augmentation cystoplasty.

Original languageEnglish (US)
Number of pages1
JournalUrology
Volume54
Issue number3
DOIs
StatePublished - Sep 1999

ASJC Scopus subject areas

  • Urology

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  • Cite this

    Docimo, S. G., Chow, N. H., Steiner, G., Silver, R. I., Rodriguez, R., Kinsman, S., Sidransky, D., & Schoenberg, M. (1999). Detection of adenocarcinoma by urinary microsatellite analysis after augmentation cystoplasty. Urology, 54(3). https://doi.org/10.1016/s0090-4295(99)00159-4