Abstract
Augmentation cystoplasty is associated with an increased risk of bladder cancer development between 10 and 20 years after augmentation. Using microsatellite analysis, we analyzed urine obtained before surgical resection of the malignant lesion from a patient who developed invasive adenocarcinoma after augmentation cystoplasty. Loss of heterozygosity was identified in both urine and tumor samples from this patient. This observation suggests that microsatellite urine analysis may be useful as a monitoring tool for patients after augmentation cystoplasty.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 561 |
| Number of pages | 1 |
| Journal | Urology |
| Volume | 54 |
| Issue number | 3 |
| State | Published - Sep 1999 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Urology
Cite this
Detection of adenocarcinoma by urinary microsatellite analysis after augmentation cystoplasty. / Docimo, S. G.; Chow, N. H.; Steiner, G.; Silver, R. I.; Rodriguez, R.; Kinsman, S.; Sidransky, D.; Schoenberg, Mark P.
In: Urology, Vol. 54, No. 3, 09.1999, p. 561.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Detection of adenocarcinoma by urinary microsatellite analysis after augmentation cystoplasty.
AU - Docimo, S. G.
AU - Chow, N. H.
AU - Steiner, G.
AU - Silver, R. I.
AU - Rodriguez, R.
AU - Kinsman, S.
AU - Sidransky, D.
AU - Schoenberg, Mark P.
PY - 1999/9
Y1 - 1999/9
N2 - Augmentation cystoplasty is associated with an increased risk of bladder cancer development between 10 and 20 years after augmentation. Using microsatellite analysis, we analyzed urine obtained before surgical resection of the malignant lesion from a patient who developed invasive adenocarcinoma after augmentation cystoplasty. Loss of heterozygosity was identified in both urine and tumor samples from this patient. This observation suggests that microsatellite urine analysis may be useful as a monitoring tool for patients after augmentation cystoplasty.
AB - Augmentation cystoplasty is associated with an increased risk of bladder cancer development between 10 and 20 years after augmentation. Using microsatellite analysis, we analyzed urine obtained before surgical resection of the malignant lesion from a patient who developed invasive adenocarcinoma after augmentation cystoplasty. Loss of heterozygosity was identified in both urine and tumor samples from this patient. This observation suggests that microsatellite urine analysis may be useful as a monitoring tool for patients after augmentation cystoplasty.
UR - http://www.scopus.com/inward/record.url?scp=0033186244&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0033186244&partnerID=8YFLogxK
M3 - Article
C2 - 10754137
AN - SCOPUS:0033186244
VL - 54
SP - 561
JO - Urology
JF - Urology
SN - 0090-4295
IS - 3
ER -