Detection of adenocarcinoma by urinary microsatellite analysis after augmentation cystoplasty.

S. G. Docimo, N. H. Chow, G. Steiner, R. I. Silver, R. Rodriguez, S. Kinsman, D. Sidransky, Mark P. Schoenberg

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Augmentation cystoplasty is associated with an increased risk of bladder cancer development between 10 and 20 years after augmentation. Using microsatellite analysis, we analyzed urine obtained before surgical resection of the malignant lesion from a patient who developed invasive adenocarcinoma after augmentation cystoplasty. Loss of heterozygosity was identified in both urine and tumor samples from this patient. This observation suggests that microsatellite urine analysis may be useful as a monitoring tool for patients after augmentation cystoplasty.

Original languageEnglish (US)
Pages (from-to)561
Number of pages1
JournalUrology
Volume54
Issue number3
StatePublished - Sep 1999
Externally publishedYes

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Microsatellite Repeats
Adenocarcinoma
Urine
Loss of Heterozygosity
Physiologic Monitoring
Urinary Bladder Neoplasms
Neoplasms

ASJC Scopus subject areas

  • Urology

Cite this

Docimo, S. G., Chow, N. H., Steiner, G., Silver, R. I., Rodriguez, R., Kinsman, S., ... Schoenberg, M. P. (1999). Detection of adenocarcinoma by urinary microsatellite analysis after augmentation cystoplasty. Urology, 54(3), 561.

Detection of adenocarcinoma by urinary microsatellite analysis after augmentation cystoplasty. / Docimo, S. G.; Chow, N. H.; Steiner, G.; Silver, R. I.; Rodriguez, R.; Kinsman, S.; Sidransky, D.; Schoenberg, Mark P.

In: Urology, Vol. 54, No. 3, 09.1999, p. 561.

Research output: Contribution to journalArticle

Docimo, SG, Chow, NH, Steiner, G, Silver, RI, Rodriguez, R, Kinsman, S, Sidransky, D & Schoenberg, MP 1999, 'Detection of adenocarcinoma by urinary microsatellite analysis after augmentation cystoplasty.', Urology, vol. 54, no. 3, pp. 561.
Docimo SG, Chow NH, Steiner G, Silver RI, Rodriguez R, Kinsman S et al. Detection of adenocarcinoma by urinary microsatellite analysis after augmentation cystoplasty. Urology. 1999 Sep;54(3):561.
Docimo, S. G. ; Chow, N. H. ; Steiner, G. ; Silver, R. I. ; Rodriguez, R. ; Kinsman, S. ; Sidransky, D. ; Schoenberg, Mark P. / Detection of adenocarcinoma by urinary microsatellite analysis after augmentation cystoplasty. In: Urology. 1999 ; Vol. 54, No. 3. pp. 561.
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