Detection of adenocarcinoma by urinary microsatellite analysis after augmentation cystoplasty.

S. G. Docimo; N. H. Chow; G. Steiner; R. I. Silver; R. Rodriguez; S. Kinsman; D. Sidransky; M. Schoenberg

doi:10.1016/s0090-4295(99)00159-4

Detection of adenocarcinoma by urinary microsatellite analysis after augmentation cystoplasty.

S. G. Docimo, N. H. Chow, G. Steiner, R. I. Silver, R. Rodriguez, S. Kinsman, D. Sidransky, M. Schoenberg

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

Augmentation cystoplasty is associated with an increased risk of bladder cancer development between 10 and 20 years after augmentation. Using microsatellite analysis, we analyzed urine obtained before surgical resection of the malignant lesion from a patient who developed invasive adenocarcinoma after augmentation cystoplasty. Loss of heterozygosity was identified in both urine and tumor samples from this patient. This observation suggests that microsatellite urine analysis may be useful as a monitoring tool for patients after augmentation cystoplasty.

Original language	English (US)
Number of pages	1
Journal	Urology
Volume	54
Issue number	3
DOIs	https://doi.org/10.1016/s0090-4295(99)00159-4
State	Published - Sep 1999
Externally published	Yes

ASJC Scopus subject areas

Urology

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title = "Detection of adenocarcinoma by urinary microsatellite analysis after augmentation cystoplasty.",

abstract = "Augmentation cystoplasty is associated with an increased risk of bladder cancer development between 10 and 20 years after augmentation. Using microsatellite analysis, we analyzed urine obtained before surgical resection of the malignant lesion from a patient who developed invasive adenocarcinoma after augmentation cystoplasty. Loss of heterozygosity was identified in both urine and tumor samples from this patient. This observation suggests that microsatellite urine analysis may be useful as a monitoring tool for patients after augmentation cystoplasty.",

author = "Docimo, {S. G.} and Chow, {N. H.} and G. Steiner and Silver, {R. I.} and R. Rodriguez and S. Kinsman and D. Sidransky and M. Schoenberg",

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AU - Docimo, S. G.

AU - Chow, N. H.

AU - Steiner, G.

AU - Silver, R. I.

AU - Rodriguez, R.

AU - Kinsman, S.

AU - Sidransky, D.

AU - Schoenberg, M.

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Y1 - 1999/9

N2 - Augmentation cystoplasty is associated with an increased risk of bladder cancer development between 10 and 20 years after augmentation. Using microsatellite analysis, we analyzed urine obtained before surgical resection of the malignant lesion from a patient who developed invasive adenocarcinoma after augmentation cystoplasty. Loss of heterozygosity was identified in both urine and tumor samples from this patient. This observation suggests that microsatellite urine analysis may be useful as a monitoring tool for patients after augmentation cystoplasty.

AB - Augmentation cystoplasty is associated with an increased risk of bladder cancer development between 10 and 20 years after augmentation. Using microsatellite analysis, we analyzed urine obtained before surgical resection of the malignant lesion from a patient who developed invasive adenocarcinoma after augmentation cystoplasty. Loss of heterozygosity was identified in both urine and tumor samples from this patient. This observation suggests that microsatellite urine analysis may be useful as a monitoring tool for patients after augmentation cystoplasty.

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