Detection and management of early diabetic nephropathy

Jill P. Crandall; Gerald B. Appel

doi:10.1016/1043-2760(93)90127-Z

Detection and management of early diabetic nephropathy

Jill P. Crandall, Gerald B. Appel

Research output: Contribution to journal › Review article › peer-review

1 Scopus citations

Abstract

It has proven difficult to alter the progression of diabetic nephropathy once overt proteinuria is established. The presence of microalbuminuria reflects an early renal lesion that may be more amenable to therapeutic intervention. Dietary protein restriction, improved glycemic control, and aggressive treatment of high blood pressure all have shown beneficial effects in some patients. Angiotensin-converting enzyme inhibitor therapy may offer specific advantages in terms of its renal protective effects.

Original language	English (US)
Pages (from-to)	232-237
Number of pages	6
Journal	Trends in Endocrinology and Metabolism
Volume	4
Issue number	7
DOIs	https://doi.org/10.1016/1043-2760(93)90127-Z
State	Published - Sep 1993
Externally published	Yes

ASJC Scopus subject areas

Endocrinology, Diabetes and Metabolism
Endocrinology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/1043-2760(93)90127-Z

Cite this

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title = "Detection and management of early diabetic nephropathy",

abstract = "It has proven difficult to alter the progression of diabetic nephropathy once overt proteinuria is established. The presence of microalbuminuria reflects an early renal lesion that may be more amenable to therapeutic intervention. Dietary protein restriction, improved glycemic control, and aggressive treatment of high blood pressure all have shown beneficial effects in some patients. Angiotensin-converting enzyme inhibitor therapy may offer specific advantages in terms of its renal protective effects.",

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AU - Crandall, Jill P.

AU - Appel, Gerald B.

PY - 1993/9

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N2 - It has proven difficult to alter the progression of diabetic nephropathy once overt proteinuria is established. The presence of microalbuminuria reflects an early renal lesion that may be more amenable to therapeutic intervention. Dietary protein restriction, improved glycemic control, and aggressive treatment of high blood pressure all have shown beneficial effects in some patients. Angiotensin-converting enzyme inhibitor therapy may offer specific advantages in terms of its renal protective effects.

AB - It has proven difficult to alter the progression of diabetic nephropathy once overt proteinuria is established. The presence of microalbuminuria reflects an early renal lesion that may be more amenable to therapeutic intervention. Dietary protein restriction, improved glycemic control, and aggressive treatment of high blood pressure all have shown beneficial effects in some patients. Angiotensin-converting enzyme inhibitor therapy may offer specific advantages in terms of its renal protective effects.

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DO - 10.1016/1043-2760(93)90127-Z

M3 - Review article

AN - SCOPUS:0027503854

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SP - 232

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JO - Trends in Endocrinology and Metabolism

JF - Trends in Endocrinology and Metabolism

IS - 7

ER -

Detection and management of early diabetic nephropathy

Abstract

ASJC Scopus subject areas

UN SDGs

Access to Document

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