Detection and management of early diabetic nephropathy

Jill P. Crandall, Gerald B. Appel

Research output: Contribution to journalReview articlepeer-review

1 Scopus citations


It has proven difficult to alter the progression of diabetic nephropathy once overt proteinuria is established. The presence of microalbuminuria reflects an early renal lesion that may be more amenable to therapeutic intervention. Dietary protein restriction, improved glycemic control, and aggressive treatment of high blood pressure all have shown beneficial effects in some patients. Angiotensin-converting enzyme inhibitor therapy may offer specific advantages in terms of its renal protective effects.

Original languageEnglish (US)
Pages (from-to)232-237
Number of pages6
JournalTrends in Endocrinology and Metabolism
Issue number7
StatePublished - Sep 1993
Externally publishedYes

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

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