The authors report results of an 8-week, open trial of desipramine in 42 patients with DSM-III-R dysthymia with a concurrent diagnosis of major depression ('double' depression) and 33 patients with dysthymia who had no other depressive diagnosis ('pure' dysthymia). Either complete or partial remission was achieved by 70% of the patients with 'pure' dysthymia. This compared favorably with but was not significantly different from results in the 'double' depression group.
ASJC Scopus subject areas
- Psychiatry and Mental health