Delivery Outcomes of Patients with Acute Migraine in Pregnancy: A Retrospective Study

Tracy B. Grossman, Matthew S. Robbins, Shravya Govindappagari, Ashlesha K. Dayal

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Objective: To describe labor and delivery outcomes in pregnant patients presenting to the hospital setting with an acute severe migraine headache attack earlier in the same gestation. Methods: We retrospectively reviewed pregnancy and delivery records from a database of consecutive inpatient neurology consultations for acute headache in pregnant women over a 5 year period. Results: We identified 86 pregnant women with acute migraine. The mean age was 29.3 (±6.4) years. Nearly half had migraine with aura (35/86 [40.7%]), 12.8% (12/86) had chronic migraine, and 31.4% (27/86) presented in status migrainosus. Complication rates included 54.7%([41/75], 95% CI 29.87, 52.13) for at least one adverse outcome, 28.0% ([21/75], 95% CI 11.78, 30.22) for preterm delivery, 21.3% ([16/75], 95% CI 7.7, 24.3) for preeclampsia, 30.6% ([23/75] 95% CI 13.48, 32.52) for cesarean delivery, and 18.7% ([14/75] 95% CI 6.15, 21.85) for low birthweight. Conclusions: Pregnant women seeking treatment for acute migraine headache experienced a higher rate of preterm delivery, preeclampsia, and low birthweight but a lower rate of cesarean delivery than the local and general populations. More than half (54.7% [41/75] 95% CI 29.87, 52.13) of the study patients experienced some type of adverse birth outcome, suggesting that pregnancies in migraine patients presenting to an acute care setting may benefit from more intense surveillance.

Original languageEnglish (US)
Pages (from-to)605-611
Number of pages7
JournalHeadache
Volume57
Issue number4
DOIs
StatePublished - Apr 1 2017

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Migraine Disorders
Retrospective Studies
Pregnancy
Pregnant Women
Pre-Eclampsia
Migraine with Aura
Pregnancy Outcome
Neurology
Headache
Inpatients
Referral and Consultation
Parturition
Databases
Population

Keywords

  • birth outcome
  • migraine
  • pregnancy

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

Cite this

Grossman, T. B., Robbins, M. S., Govindappagari, S., & Dayal, A. K. (2017). Delivery Outcomes of Patients with Acute Migraine in Pregnancy: A Retrospective Study. Headache, 57(4), 605-611. https://doi.org/10.1111/head.13023

Delivery Outcomes of Patients with Acute Migraine in Pregnancy : A Retrospective Study. / Grossman, Tracy B.; Robbins, Matthew S.; Govindappagari, Shravya; Dayal, Ashlesha K.

In: Headache, Vol. 57, No. 4, 01.04.2017, p. 605-611.

Research output: Contribution to journalArticle

Grossman, TB, Robbins, MS, Govindappagari, S & Dayal, AK 2017, 'Delivery Outcomes of Patients with Acute Migraine in Pregnancy: A Retrospective Study', Headache, vol. 57, no. 4, pp. 605-611. https://doi.org/10.1111/head.13023
Grossman, Tracy B. ; Robbins, Matthew S. ; Govindappagari, Shravya ; Dayal, Ashlesha K. / Delivery Outcomes of Patients with Acute Migraine in Pregnancy : A Retrospective Study. In: Headache. 2017 ; Vol. 57, No. 4. pp. 605-611.
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abstract = "Objective: To describe labor and delivery outcomes in pregnant patients presenting to the hospital setting with an acute severe migraine headache attack earlier in the same gestation. Methods: We retrospectively reviewed pregnancy and delivery records from a database of consecutive inpatient neurology consultations for acute headache in pregnant women over a 5 year period. Results: We identified 86 pregnant women with acute migraine. The mean age was 29.3 (±6.4) years. Nearly half had migraine with aura (35/86 [40.7{\%}]), 12.8{\%} (12/86) had chronic migraine, and 31.4{\%} (27/86) presented in status migrainosus. Complication rates included 54.7{\%}([41/75], 95{\%} CI 29.87, 52.13) for at least one adverse outcome, 28.0{\%} ([21/75], 95{\%} CI 11.78, 30.22) for preterm delivery, 21.3{\%} ([16/75], 95{\%} CI 7.7, 24.3) for preeclampsia, 30.6{\%} ([23/75] 95{\%} CI 13.48, 32.52) for cesarean delivery, and 18.7{\%} ([14/75] 95{\%} CI 6.15, 21.85) for low birthweight. Conclusions: Pregnant women seeking treatment for acute migraine headache experienced a higher rate of preterm delivery, preeclampsia, and low birthweight but a lower rate of cesarean delivery than the local and general populations. More than half (54.7{\%} [41/75] 95{\%} CI 29.87, 52.13) of the study patients experienced some type of adverse birth outcome, suggesting that pregnancies in migraine patients presenting to an acute care setting may benefit from more intense surveillance.",
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N2 - Objective: To describe labor and delivery outcomes in pregnant patients presenting to the hospital setting with an acute severe migraine headache attack earlier in the same gestation. Methods: We retrospectively reviewed pregnancy and delivery records from a database of consecutive inpatient neurology consultations for acute headache in pregnant women over a 5 year period. Results: We identified 86 pregnant women with acute migraine. The mean age was 29.3 (±6.4) years. Nearly half had migraine with aura (35/86 [40.7%]), 12.8% (12/86) had chronic migraine, and 31.4% (27/86) presented in status migrainosus. Complication rates included 54.7%([41/75], 95% CI 29.87, 52.13) for at least one adverse outcome, 28.0% ([21/75], 95% CI 11.78, 30.22) for preterm delivery, 21.3% ([16/75], 95% CI 7.7, 24.3) for preeclampsia, 30.6% ([23/75] 95% CI 13.48, 32.52) for cesarean delivery, and 18.7% ([14/75] 95% CI 6.15, 21.85) for low birthweight. Conclusions: Pregnant women seeking treatment for acute migraine headache experienced a higher rate of preterm delivery, preeclampsia, and low birthweight but a lower rate of cesarean delivery than the local and general populations. More than half (54.7% [41/75] 95% CI 29.87, 52.13) of the study patients experienced some type of adverse birth outcome, suggesting that pregnancies in migraine patients presenting to an acute care setting may benefit from more intense surveillance.

AB - Objective: To describe labor and delivery outcomes in pregnant patients presenting to the hospital setting with an acute severe migraine headache attack earlier in the same gestation. Methods: We retrospectively reviewed pregnancy and delivery records from a database of consecutive inpatient neurology consultations for acute headache in pregnant women over a 5 year period. Results: We identified 86 pregnant women with acute migraine. The mean age was 29.3 (±6.4) years. Nearly half had migraine with aura (35/86 [40.7%]), 12.8% (12/86) had chronic migraine, and 31.4% (27/86) presented in status migrainosus. Complication rates included 54.7%([41/75], 95% CI 29.87, 52.13) for at least one adverse outcome, 28.0% ([21/75], 95% CI 11.78, 30.22) for preterm delivery, 21.3% ([16/75], 95% CI 7.7, 24.3) for preeclampsia, 30.6% ([23/75] 95% CI 13.48, 32.52) for cesarean delivery, and 18.7% ([14/75] 95% CI 6.15, 21.85) for low birthweight. Conclusions: Pregnant women seeking treatment for acute migraine headache experienced a higher rate of preterm delivery, preeclampsia, and low birthweight but a lower rate of cesarean delivery than the local and general populations. More than half (54.7% [41/75] 95% CI 29.87, 52.13) of the study patients experienced some type of adverse birth outcome, suggesting that pregnancies in migraine patients presenting to an acute care setting may benefit from more intense surveillance.

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