Deficiency of the DNA repair protein nibrin increases the basal but not the radiation induced mutation frequency in vivo

Medicine & Life Sciences

• DNA Repair-Deficiency Disorders 100%
• Mutation Rate 72%
• Radiation 51%
• Mutation 38%
• Radiation Tolerance 26%
• Double-Stranded DNA Breaks 26%
• Proteins 25%
• DNA Damage 19%
• In Vitro Techniques 14%
• Lymphatic System 14%
• Loss of Function Mutation 12%
• Lymphoid Tissue 12%
• DNA Replication 11%
• DNA Repair 10%
• Plasmids 9%
• Cell Cycle 8%
• Fibroblasts 8%
• Apoptosis 6%
• Neoplasms 3%

Chemical Compounds

• Mutation 57%
• Protein 28%
• Disorder 5%
• Error 4%