Deferred parathyroid autografts with cryopreserved tissue after reoperative parathyroid surgery

A. W. Saxe, Allen M. Spiegel, S. J. Marx, M. F. Brenman

Research output: Contribution to journalArticle

40 Citations (Scopus)

Abstract

Between August 1975 and March 1981, 12 patients underwent forearm parathyroid autotransplantation with cryopreserved tissue following reoperative parathyroid surgery. Tissue had been cryopreserved two to 18 months. Follow-up ranged from four to 66 months (median, 18 months) following autotransplantation. All patients required calcium supplementation as a condition for autografting; six patients were no longer receiving calcium supplementation at most recent follow-up and in one patient the dosage was being tapered. The presence of a parathyroid hormone gradient of 2:1 or greater correlated well with freedom from calcium supplementation. Of seven patients with preautograft and postautograft urinary cyclic adenosine monophosphate (cAMP) determinations, three with increases following transplantation did not require calcium, three without increases continued to require calcium, and the patient whose dosage was being tapered had increased urinary cAMP levels.

Original languageEnglish (US)
Pages (from-to)538-543
Number of pages6
JournalArchives of Surgery
Volume117
Issue number5
StatePublished - 1982
Externally publishedYes

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Autografts
Autologous Transplantation
Calcium
Cyclic AMP
Parathyroid Hormone
Forearm
Transplantation

ASJC Scopus subject areas

  • Surgery

Cite this

Deferred parathyroid autografts with cryopreserved tissue after reoperative parathyroid surgery. / Saxe, A. W.; Spiegel, Allen M.; Marx, S. J.; Brenman, M. F.

In: Archives of Surgery, Vol. 117, No. 5, 1982, p. 538-543.

Research output: Contribution to journalArticle

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