Deciphering structural bases of intestinal and hepatic selectivity in targeting pregnane X receptor with indole-based microbial mimics

Hao Li, Peter Illés, Chamini V. Karunaratne, Lars Ulrik Nordstrøm, Xiaoping Luo, Annie Yang, Yunping Qiu, Irwin J. Kurland, Dana J. Lukin, Weijie Chen, Eva Jiskrová, Kristýna Krasulová, Petra Pečinková, Vera M. DesMarais, Qiang Liu, Joseph M. Albanese, Ashwin Akki, Michael Longo, Breyen Coffin, Vivi DouSridhar Mani, Zdeněk Dvořák

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Chemical Compounds

Medicine & Life Sciences