Cytomegalovirus colitis in acquired immune deficiency syndrome: Radiologic spectrum

David H. Frager, Joseph D. Frager, Ellen L. Wolf, Lawrence G. Rand, Geraldine St Onge, Sumi Mitsudo, Leonard Bodner, Lawrence J. Brandt, Thomas C. Beneventano

Research output: Contribution to journalArticle

33 Scopus citations

Abstract

Six cases of cytomegalovirus (CMV) colitis are described. The radiographic manifestations of this colitis are nonspecific and usually mimic the findings of ulcerative colitis with diffuse mucosal ulceration or granulomatous colitis with aphthous ulceration and skip areas. Terminal ileal involvement was noted in 1 patient. Nonspecific edema was present in 2 other cases. One patient demonstrated unusual cecal and ascending colonic nodularity due to pseudomembranes and, in another, large flat discrete ulcerations were identified. Angiography, in 1 case, demonstrated marked hypervascularity and identified a site of hemorrhage in the ascending colon. With the radiographic identification of colitis in an immunocompromised patient, particularly a patient with acquired immunodeficiency syndrome (AIDS), CMV colitis must be strongly considered in the differential diagnosis. Endoscopic biopsy is the most effective method of establishing the diagnosis.

Original languageEnglish (US)
Pages (from-to)241-246
Number of pages6
JournalGastrointestinal Radiology
Volume11
Issue number1
DOIs
StatePublished - Jan 1 1986

Keywords

  • Acquired immunodeficiency syndrome (AIDS)
  • Cytomegalovirus colitis

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Gastroenterology

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    Frager, D. H., Frager, J. D., Wolf, E. L., Rand, L. G., Onge, G. S., Mitsudo, S., Bodner, L., Brandt, L. J., & Beneventano, T. C. (1986). Cytomegalovirus colitis in acquired immune deficiency syndrome: Radiologic spectrum. Gastrointestinal Radiology, 11(1), 241-246. https://doi.org/10.1007/BF02035081