Cytogenetic damage in peripheral blood lymphocytes of cancer patients prior to radiotherapy

K.h. Ramesh, M. K. Bhargava

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

In a study comprised of 79 cancer patients selected for determining chromosomal damage to peripheral blood lymphocytes before, during, and after radiotherapy, four patients revealed chromosome aberrations prior to radiotherapy in 5% of the cells examined. The most common anomalies were dicentric chromosomes and translocations of unidentified chromosomal material on the long or short arm. We attribute this high incidence of chromosomal aberrations before radiotherapy to a combination of various external factors that are known to cause such cytogenetic injury.

Original languageEnglish (US)
Pages (from-to)86-88
Number of pages3
JournalCancer Genetics and Cytogenetics
Volume60
Issue number1
DOIs
StatePublished - 1992
Externally publishedYes

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Cytogenetics
Radiotherapy
Lymphocytes
Chromosome Aberrations
Neoplasms
Genetic Translocation
Chromosomes
Incidence
Wounds and Injuries

ASJC Scopus subject areas

  • Cancer Research
  • Genetics
  • Molecular Biology

Cite this

Cytogenetic damage in peripheral blood lymphocytes of cancer patients prior to radiotherapy. / Ramesh, K.h.; Bhargava, M. K.

In: Cancer Genetics and Cytogenetics, Vol. 60, No. 1, 1992, p. 86-88.

Research output: Contribution to journalArticle

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