Cytogenetic damage in peripheral blood lymphocytes of cancer patients prior to radiotherapy

K. H. Ramesh, M. K. Bhargava

Research output: Contribution to journalArticle

12 Scopus citations

Abstract

In a study comprised of 79 cancer patients selected for determining chromosomal damage to peripheral blood lymphocytes before, during, and after radiotherapy, four patients revealed chromosome aberrations prior to radiotherapy in 5% of the cells examined. The most common anomalies were dicentric chromosomes and translocations of unidentified chromosomal material on the long or short arm. We attribute this high incidence of chromosomal aberrations before radiotherapy to a combination of various external factors that are known to cause such cytogenetic injury.

Original languageEnglish (US)
Pages (from-to)86-88
Number of pages3
JournalCancer Genetics and Cytogenetics
Volume60
Issue number1
DOIs
StatePublished - May 1992
Externally publishedYes

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics
  • Cancer Research

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