Abstract
Multikinase inhibitors have become first-line agents for treatment of multiple systemic cancers. These agents are very effective but can also cause a variety of toxicities affecting the skin, hair, and nails. One of the most common reactions is the hand-foot skin reaction, distinct from hand-foot syndrome caused by more traditional chemotherapy agents. All of these cutaneous reactions can negatively affect patients' quality of life and can lead to dose modifications and treatment interruptions. This article reviews the cutaneous toxicities from sorafenib and sunitinib with emphasis on treatment strategies.
Original language | English (US) |
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Pages (from-to) | 396-400 |
Number of pages | 5 |
Journal | Dermatologic Therapy |
Volume | 24 |
Issue number | 4 |
DOIs | |
State | Published - Jul 2011 |
Externally published | Yes |
Keywords
- hand-foot skin reaction
- sorafenib
- sunitinib
ASJC Scopus subject areas
- Dermatology