Current management of advanced resectable oral cavity squamous cell carcinoma

Thomas J. Ow, Jeffrey N. Myers

Research output: Contribution to journalReview article

26 Scopus citations

Abstract

The oral cavity is the most common site of head and neck squamous cell carcinoma, a disease which results in significant morbidity and mortality worldwide. Though the primary modality of treatment for patients with oral cavity cancer remains surgical resection, many patients present with advanced disease and are thus treated using a multi-disciplinary approach. Patients with extracapsular spread of lymphatic metastasis and surgical margins that remain positive have been found to be at high risk for local-regional recurrence and death from disease, and are most often recommended to receive both postoperative radiation as well as systemic chemotherapy. The basis for this approach, as well as scientific developments that underly future trials of novels treatments for patients with high-risk oral cavity cancer are reviewed.

Original languageEnglish (US)
Pages (from-to)1-10
Number of pages10
JournalClinical and Experimental Otorhinolaryngology
Volume4
Issue number1
DOIs
StatePublished - Mar 1 2011
Externally publishedYes

Keywords

  • Chemotherapy
  • Head and neck neoplasms
  • Oral cancer
  • Radiotherapy
  • Surgery
  • Treatment

ASJC Scopus subject areas

  • Surgery
  • Otorhinolaryngology

Fingerprint Dive into the research topics of 'Current management of advanced resectable oral cavity squamous cell carcinoma'. Together they form a unique fingerprint.

Cite this