Abstract
Gram-negative bacteria are the dominant killers among bacterial pathogens in the intensive care unit. Antibiotic resistance has become a threat in hospital settings and efforts are being made to understand the underlying mechanisms. This review describes current data on the most important mechanisms of resistance in prevalent Gram-negative pathogens as well as newer therapeutic options.
Original language | English (US) |
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Pages (from-to) | 833-843 |
Number of pages | 11 |
Journal | Expert Review of Anti-Infective Therapy |
Volume | 5 |
Issue number | 5 |
DOIs | |
State | Published - Oct 2007 |
Externally published | Yes |
Keywords
- Bacterial resistance
- Carbapenems
- Gram-negatives
- Mechanisms of resistance
- Tigecycline
ASJC Scopus subject areas
- Microbiology
- Microbiology (medical)
- Virology
- Infectious Diseases