Current concepts in antibiotic-resistant Gram-negative bacteria

Julián Andrés Torres, Maria Virginia Villegas, John P. Quinn

Research output: Contribution to journalReview articlepeer-review

35 Scopus citations


Gram-negative bacteria are the dominant killers among bacterial pathogens in the intensive care unit. Antibiotic resistance has become a threat in hospital settings and efforts are being made to understand the underlying mechanisms. This review describes current data on the most important mechanisms of resistance in prevalent Gram-negative pathogens as well as newer therapeutic options.

Original languageEnglish (US)
Pages (from-to)833-843
Number of pages11
JournalExpert Review of Anti-Infective Therapy
Issue number5
StatePublished - Oct 2007
Externally publishedYes


  • Bacterial resistance
  • Carbapenems
  • Gram-negatives
  • Mechanisms of resistance
  • Tigecycline

ASJC Scopus subject areas

  • Microbiology
  • Microbiology (medical)
  • Virology
  • Infectious Diseases


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