Cuban Americans have the highest rates of peripheral arterial disease in diverse Hispanic/Latino communities

Matthew A. Allison, Franklyn Gonzalez, Leopoldo Raij, Robert C. Kaplan, Robert J Ostfeld, Maria S. Pattany, Gerardo Heiss, Michael H. Criqui

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Objective Because Hispanic ethnicity in the United States is heterogeneous, the purpose of this study was to determine the epidemiology of peripheral arterial disease (PAD) within U.S. Hispanic/Latino groups defined by national background. Methods This analysis included 9648 men and women older than 45 years enrolled in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL). The ankle-brachial index (ABI) was computed as the higher of the posterior tibial and dorsalis pedis systolic blood pressures for each leg divided by the higher brachial artery systolic blood pressure. The index ABI was the higher of the two. An ABI ≤0.90 was the criterion for the presence of PAD. Results The mean age was 56 years, and 55% were female. Overall, the prevalence of an ABI ≤0.90 (PAD), 0.90 to 0.99 (borderline), 1.0 to 1.39 (normal), and ≥1.40 (high) was 5.7%, 19.3%, 72.5%, and 2.6%, respectively. After multivariable adjustment for PAD risk factors and compared with Mexicans, Cubans had a nearly threefold higher odds for PAD (odds ratio, 2.9; 95% confidence interval, 1.9-4.4). The odds of PAD for the other Hispanic/Latino groups ranged from 1.2 to 1.8. Although men had a more than threefold higher odds of an ABI ≥1.40 (3.6; 2.0-6.5), the odds did not differ significantly by Hispanic/Latino background. Conclusions Compared with Mexican Americans, all other Hispanic/Latino background groups have a significantly higher odds of having PAD, with the odds being nearly threefold higher among Cubans.

Original languageEnglish (US)
Pages (from-to)665-672
Number of pages8
JournalJournal of Vascular Surgery
Volume62
Issue number3
DOIs
StatePublished - Sep 1 2015

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Peripheral Arterial Disease
Hispanic Americans
Ankle Brachial Index
Blood Pressure
Brachial Artery
Leg
Epidemiology
Odds Ratio
Confidence Intervals

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Surgery

Cite this

Cuban Americans have the highest rates of peripheral arterial disease in diverse Hispanic/Latino communities. / Allison, Matthew A.; Gonzalez, Franklyn; Raij, Leopoldo; Kaplan, Robert C.; Ostfeld, Robert J; Pattany, Maria S.; Heiss, Gerardo; Criqui, Michael H.

In: Journal of Vascular Surgery, Vol. 62, No. 3, 01.09.2015, p. 665-672.

Research output: Contribution to journalArticle

Allison, Matthew A. ; Gonzalez, Franklyn ; Raij, Leopoldo ; Kaplan, Robert C. ; Ostfeld, Robert J ; Pattany, Maria S. ; Heiss, Gerardo ; Criqui, Michael H. / Cuban Americans have the highest rates of peripheral arterial disease in diverse Hispanic/Latino communities. In: Journal of Vascular Surgery. 2015 ; Vol. 62, No. 3. pp. 665-672.
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abstract = "Objective Because Hispanic ethnicity in the United States is heterogeneous, the purpose of this study was to determine the epidemiology of peripheral arterial disease (PAD) within U.S. Hispanic/Latino groups defined by national background. Methods This analysis included 9648 men and women older than 45 years enrolled in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL). The ankle-brachial index (ABI) was computed as the higher of the posterior tibial and dorsalis pedis systolic blood pressures for each leg divided by the higher brachial artery systolic blood pressure. The index ABI was the higher of the two. An ABI ≤0.90 was the criterion for the presence of PAD. Results The mean age was 56 years, and 55{\%} were female. Overall, the prevalence of an ABI ≤0.90 (PAD), 0.90 to 0.99 (borderline), 1.0 to 1.39 (normal), and ≥1.40 (high) was 5.7{\%}, 19.3{\%}, 72.5{\%}, and 2.6{\%}, respectively. After multivariable adjustment for PAD risk factors and compared with Mexicans, Cubans had a nearly threefold higher odds for PAD (odds ratio, 2.9; 95{\%} confidence interval, 1.9-4.4). The odds of PAD for the other Hispanic/Latino groups ranged from 1.2 to 1.8. Although men had a more than threefold higher odds of an ABI ≥1.40 (3.6; 2.0-6.5), the odds did not differ significantly by Hispanic/Latino background. Conclusions Compared with Mexican Americans, all other Hispanic/Latino background groups have a significantly higher odds of having PAD, with the odds being nearly threefold higher among Cubans.",
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AB - Objective Because Hispanic ethnicity in the United States is heterogeneous, the purpose of this study was to determine the epidemiology of peripheral arterial disease (PAD) within U.S. Hispanic/Latino groups defined by national background. Methods This analysis included 9648 men and women older than 45 years enrolled in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL). The ankle-brachial index (ABI) was computed as the higher of the posterior tibial and dorsalis pedis systolic blood pressures for each leg divided by the higher brachial artery systolic blood pressure. The index ABI was the higher of the two. An ABI ≤0.90 was the criterion for the presence of PAD. Results The mean age was 56 years, and 55% were female. Overall, the prevalence of an ABI ≤0.90 (PAD), 0.90 to 0.99 (borderline), 1.0 to 1.39 (normal), and ≥1.40 (high) was 5.7%, 19.3%, 72.5%, and 2.6%, respectively. After multivariable adjustment for PAD risk factors and compared with Mexicans, Cubans had a nearly threefold higher odds for PAD (odds ratio, 2.9; 95% confidence interval, 1.9-4.4). The odds of PAD for the other Hispanic/Latino groups ranged from 1.2 to 1.8. Although men had a more than threefold higher odds of an ABI ≥1.40 (3.6; 2.0-6.5), the odds did not differ significantly by Hispanic/Latino background. Conclusions Compared with Mexican Americans, all other Hispanic/Latino background groups have a significantly higher odds of having PAD, with the odds being nearly threefold higher among Cubans.

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