Abstract
We have crystallized the N-terminal actin binding domain (ABD1) of human fimbrin, a representative member of the largest class of actin crosslinking proteins. Diffraction from these crystals is consistent with the orthorhombic space group P212121 (α = 50.03 Å, b = 61.24 Å, c = 102.30 Å). These crystals contain one molecule in the asymmetric unit and diffract to at least 1.9 Å resolution. The crystal structure of ABD1 will be the first structure of an actin crosslinking domain.
Original language | English (US) |
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Pages (from-to) | 452-453 |
Number of pages | 2 |
Journal | Proteins: Structure, Function and Genetics |
Volume | 28 |
Issue number | 3 |
DOIs | |
State | Published - 1997 |
Keywords
- Actin binding
- Crystallography
- F-actin crosslinker
- Fimbrin
ASJC Scopus subject areas
- Structural Biology
- Biochemistry
- Molecular Biology