Cryptococcus neoformans-Specific and Non-Cryptococcus neoformans-Specific Antibody Profiles in Organ Transplant Recipients with and Without Cryptococcosis

Hyun Ah Yoon, Antonio Nakouzi, Peter G. Pappas, Vagish S. Hemmige, Liise Anne Pirofski

Research output: Contribution to journalArticlepeer-review

Abstract

Antibody immunity has not been studied in organ transplant recipients (OTRs) with cryptococcosis. We determined serum antibody levels in OTRs: 23 cryptococcosis cases and 21 controls. Glucuronoxylomannan immunoglobulin M (IgM) and laminarin IgM were lower in cases than controls, were inversely associated with cryptococcosis status, and may hold promise as markers of cryptococcosis.

Original languageEnglish (US)
Article numberofac211
JournalOpen Forum Infectious Diseases
Volume9
Issue number7
DOIs
StatePublished - Jul 1 2022

Keywords

  • cryptococcosis
  • glucuronoxylomannan
  • IgM
  • laminarin
  • transplant recipients

ASJC Scopus subject areas

  • Oncology
  • Infectious Diseases

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