Cryptococcal Disease in HIV-Infected Children

Carol Kao, David L. Goldman

Research output: Contribution to journalReview article

6 Scopus citations

Abstract

Cryptococcus neoformans is an encapsulated fungal pathogen that is remarkable for its tendency to cause meningoencephalitis, especially in patients with AIDS. While disease is less common in children than adults, it remains an important cause of morbidity and mortality among HIV-infected children without access to anti-retroviral therapy. This review highlights recent insights into both the biology and treatment of cryptococcosis with a special emphasis on the pediatric literature.

Original languageEnglish (US)
Article number27
JournalCurrent Infectious Disease Reports
Volume18
Issue number9
DOIs
StatePublished - Sep 1 2016

Keywords

  • AIDS
  • Cryptococcosis
  • Immune reconstitution inflammatory syndrome (IRIS)
  • Increased intracranial pressure
  • Meningoencephalitis

ASJC Scopus subject areas

  • Infectious Diseases

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