Covid‑19 in Northern Italy: An integrative overview of factors possibly influencing the sharp increase of the outbreak (Review)

Marina Goumenou, Dimosthenis Sarigiannis, Aristidis Tsatsakis, Ourania Anesti, Anca Oana Docea, Dimitrios Petrakis, Dimitris Tsoukalas, Ronald Kostoff, Valeri Rakitskii, Demetrios A. Spandidos, Michael Aschner, Daniela Calina

Research output: Contribution to journalReview article

14 Scopus citations

Abstract

Italy is currently one of the countries seriously affected by the COVID-19 pandemic. As per 10 April 2020, 147,577 people were found positive in a total of 906,864 tests performed and 18,849 people lost their lives. Among all cases, 70.2% of positive, and 79.4% of deaths occurred in the provinces of Northern Italy (Lombardi, Emilia Romagna, Veneto and Piemonte), where the outbreak first started. Originally, it was considered that the high number of positive cases and deaths in Italy resulted from COVID-19 initially coming to Italy from China, its presumed country of origin. However, an analysis of the factors that played a role in the extent of this outbreak is needed. Evaluating which factors could be specific for a country and which might contribute the most is nevertheless complex, with accompanying high uncertainty. The purpose of this work is to discuss some of the possible contributing factors and their possible role in the relatively high infection and death rates in Northern Italy compared to other areas and countries.

Original languageEnglish (US)
Pages (from-to)20-32
Number of pages13
JournalMolecular Medicine Reports
Volume22
Issue number1
DOIs
StatePublished - Jul 2020

Keywords

  • COVID-19
  • Coronavirus
  • Italy
  • Pandemic diseases
  • Public health
  • Risk factors
  • SARS-CoV-2

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Medicine
  • Molecular Biology
  • Genetics
  • Oncology
  • Cancer Research

Fingerprint Dive into the research topics of 'Covid‑19 in Northern Italy: An integrative overview of factors possibly influencing the sharp increase of the outbreak (Review)'. Together they form a unique fingerprint.

  • Cite this

    Goumenou, M., Sarigiannis, D., Tsatsakis, A., Anesti, O., Docea, A. O., Petrakis, D., Tsoukalas, D., Kostoff, R., Rakitskii, V., Spandidos, D. A., Aschner, M., & Calina, D. (2020). Covid‑19 in Northern Italy: An integrative overview of factors possibly influencing the sharp increase of the outbreak (Review). Molecular Medicine Reports, 22(1), 20-32. https://doi.org/10.3892/mmr.2020.11079