COVID-19 in Children With Kidney Disease: A Report of 2 Cases

Abby Basalely, Kaye Brathwaite, Minh Dien Duong, Diane Liu, Alexandra Mazo, Yuping Xie, Marcela Del Rio, Beatrice Goilav, Nicole Hayde, Frederick J. Kaskel, Anna Zolotnitskaya, Kimberly J. Reidy

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

The presentation of novel coronavirus disease 2019 (COVID-19) in children with kidney disease is largely unknown. We report on 2 children with kidney disease not receiving long-term immunosuppression who were hospitalized due to COVID-19. The first case is an infant with end-stage kidney disease secondary to bilateral cystic dysplastic kidneys and posterior urethral valves receiving peritoneal dialysis, with a history of prematurity previously requiring mechanical ventilation in the neonatal intensive care unit, who presented with fever, hypertension, and emesis. He had no respiratory symptoms and recovered with supportive care. His hypertension was managed well with amlodipine. The second case is a child with steroid-sensitive nephrotic syndrome who presented with a relapse of nephrotic syndrome with concurrent peritonitis and sepsis caused by Streptococcus agalactiae. He was treated with antibiotics and prophylactic anticoagulation therspy. Steroid therapy was initiated after 48 hours of antibiotic therapy. Neither child required mechanical ventilation or developed COVID-19–related multisystem inflammatory syndrome.

Original languageEnglish (US)
Pages (from-to)120-123
Number of pages4
JournalKidney Medicine
Volume3
Issue number1
DOIs
StatePublished - Jan 1 2021
Externally publishedYes

Keywords

  • COVID19
  • coronavirus
  • end-stage kidney disease
  • nephrotic syndrome
  • pediatric

ASJC Scopus subject areas

  • Internal Medicine
  • Nephrology

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