COVID-19-Associated inflammatory syndrome in an adult woman with unexplained multiple organ failure: Staying vigilant for COVID-19 complications as the pandemic surges

Maedeh Veyseh, Patrick Webster, Irene Blanco

Research output: Contribution to journalArticlepeer-review

Abstract

Since the emergence of SARS-CoV-2, clinicians have been challenged with a wide spectrum of disease severity. One of the serious complications associated with the virus is multisystem inflammatory syndrome in children (MIS-C). It is characterised by inflammation leading to organ damage, in the setting of positive SARS-CoV-2 infection. MIS-C is thought to be a postviral reaction where most children are negative on PCR testing but are positive for SARS-CoV-2 antibodies. The Centers for Disease Control and Prevention recently defined the same phenomenon occurring in adults as multisystem inflammatory syndrome in adults (MIS-A) and emphasised on the use of antibody testing in this population. Here we describe an adult woman with an exposure to SARS-CoV-2 who presented with unexplained organ failure and shock. Positive antibody testing was the only clue to the diagnosis of MIS-A. We stress the importance of SARS-CoV-2 antibody detection in order to identify these cases.

Original languageEnglish (US)
Article numbere242034
JournalBMJ case reports
Volume14
Issue number4
DOIs
StatePublished - Apr 12 2021

Keywords

  • COVID-19
  • medical management

ASJC Scopus subject areas

  • Medicine(all)

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