Abstract
Objective: To quantify the cost differences and predictors of lost productive time (LPT) in persons with chronic migraine (CM) and episodic migraine (EM). Methods: The American Migraine Prevalence and Prevention (AMPP) study is a US national longitudinal survey of severe headache. Cost estimates were obtained via U.S. Census income data. To elucidate the unique predictors of LPT, the optimal distribution for modeling was determined. Zero inflation models for LPT were predicted from sociodemographics, headache features, characteristics and disability, medication use, and depression. The interaction between headache status and age was the primary effect of interest. Results: The eligible sample included 6329 persons with EM and 374 persons with CM. Men with CM aged 45 to 54 years cost employers nearly $200 per week more than do their EM counterparts. Likewise, for women, costs were higher for CM, with the cost differential between EM and CM being $90 per week. After comprehensive adjustment, increases in LPT with age were significantly higher in CM than in EM (rate ratio 1.03; 95% confidence interval 1.01-1.05). When age was recoded to a decade, metric rates of LPT increased 25% more per decade for CM than for EM (rate ratio 1.25; 95% confidence interval 1.004-1.5). Conclusions: LPT is more costly and increases more rapidly for those with CM than for those with EM as age increases.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 31-38 |
| Number of pages | 8 |
| Journal | Value in Health |
| Volume | 16 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jan 2013 |
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Keywords
- absenteeism
- chronic migraine
- cost
- episodic migraine
- lost productive time
- migraine
- presenteeism
ASJC Scopus subject areas
- Health Policy
- Public Health, Environmental and Occupational Health
Cite this
Cost and predictors of lost productive time in chronic migraine and episodic migraine : Results from the American Migraine Prevalence and Prevention (AMPP) Study. / Serrano, Daniel; Manack, Aubrey N.; Reed, Michael L.; Buse, Dawn C.; Varon, Sepideh F.; Lipton, Richard B.
In: Value in Health, Vol. 16, No. 1, 01.2013, p. 31-38.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Cost and predictors of lost productive time in chronic migraine and episodic migraine
T2 - Results from the American Migraine Prevalence and Prevention (AMPP) Study
AU - Serrano, Daniel
AU - Manack, Aubrey N.
AU - Reed, Michael L.
AU - Buse, Dawn C.
AU - Varon, Sepideh F.
AU - Lipton, Richard B.
PY - 2013/1
Y1 - 2013/1
N2 - Objective: To quantify the cost differences and predictors of lost productive time (LPT) in persons with chronic migraine (CM) and episodic migraine (EM). Methods: The American Migraine Prevalence and Prevention (AMPP) study is a US national longitudinal survey of severe headache. Cost estimates were obtained via U.S. Census income data. To elucidate the unique predictors of LPT, the optimal distribution for modeling was determined. Zero inflation models for LPT were predicted from sociodemographics, headache features, characteristics and disability, medication use, and depression. The interaction between headache status and age was the primary effect of interest. Results: The eligible sample included 6329 persons with EM and 374 persons with CM. Men with CM aged 45 to 54 years cost employers nearly $200 per week more than do their EM counterparts. Likewise, for women, costs were higher for CM, with the cost differential between EM and CM being $90 per week. After comprehensive adjustment, increases in LPT with age were significantly higher in CM than in EM (rate ratio 1.03; 95% confidence interval 1.01-1.05). When age was recoded to a decade, metric rates of LPT increased 25% more per decade for CM than for EM (rate ratio 1.25; 95% confidence interval 1.004-1.5). Conclusions: LPT is more costly and increases more rapidly for those with CM than for those with EM as age increases.
AB - Objective: To quantify the cost differences and predictors of lost productive time (LPT) in persons with chronic migraine (CM) and episodic migraine (EM). Methods: The American Migraine Prevalence and Prevention (AMPP) study is a US national longitudinal survey of severe headache. Cost estimates were obtained via U.S. Census income data. To elucidate the unique predictors of LPT, the optimal distribution for modeling was determined. Zero inflation models for LPT were predicted from sociodemographics, headache features, characteristics and disability, medication use, and depression. The interaction between headache status and age was the primary effect of interest. Results: The eligible sample included 6329 persons with EM and 374 persons with CM. Men with CM aged 45 to 54 years cost employers nearly $200 per week more than do their EM counterparts. Likewise, for women, costs were higher for CM, with the cost differential between EM and CM being $90 per week. After comprehensive adjustment, increases in LPT with age were significantly higher in CM than in EM (rate ratio 1.03; 95% confidence interval 1.01-1.05). When age was recoded to a decade, metric rates of LPT increased 25% more per decade for CM than for EM (rate ratio 1.25; 95% confidence interval 1.004-1.5). Conclusions: LPT is more costly and increases more rapidly for those with CM than for those with EM as age increases.
KW - absenteeism
KW - chronic migraine
KW - cost
KW - episodic migraine
KW - lost productive time
KW - migraine
KW - presenteeism
UR - http://www.scopus.com/inward/record.url?scp=84872741624&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84872741624&partnerID=8YFLogxK
U2 - 10.1016/j.jval.2012.08.2212
DO - 10.1016/j.jval.2012.08.2212
M3 - Article
C2 - 23337213
AN - SCOPUS:84872741624
VL - 16
SP - 31
EP - 38
JO - Value in Health
JF - Value in Health
SN - 1098-3015
IS - 1
ER -