Cost and predictors of lost productive time in chronic migraine and episodic migraine: Results from the American Migraine Prevalence and Prevention (AMPP) Study

Daniel Serrano, Aubrey N. Manack, Michael L. Reed, Dawn C. Buse, Sepideh F. Varon, Richard B. Lipton

Research output: Contribution to journalArticle

50 Citations (Scopus)

Abstract

Objective: To quantify the cost differences and predictors of lost productive time (LPT) in persons with chronic migraine (CM) and episodic migraine (EM). Methods: The American Migraine Prevalence and Prevention (AMPP) study is a US national longitudinal survey of severe headache. Cost estimates were obtained via U.S. Census income data. To elucidate the unique predictors of LPT, the optimal distribution for modeling was determined. Zero inflation models for LPT were predicted from sociodemographics, headache features, characteristics and disability, medication use, and depression. The interaction between headache status and age was the primary effect of interest. Results: The eligible sample included 6329 persons with EM and 374 persons with CM. Men with CM aged 45 to 54 years cost employers nearly $200 per week more than do their EM counterparts. Likewise, for women, costs were higher for CM, with the cost differential between EM and CM being $90 per week. After comprehensive adjustment, increases in LPT with age were significantly higher in CM than in EM (rate ratio 1.03; 95% confidence interval 1.01-1.05). When age was recoded to a decade, metric rates of LPT increased 25% more per decade for CM than for EM (rate ratio 1.25; 95% confidence interval 1.004-1.5). Conclusions: LPT is more costly and increases more rapidly for those with CM than for those with EM as age increases.

Original languageEnglish (US)
Pages (from-to)31-38
Number of pages8
JournalValue in Health
Volume16
Issue number1
DOIs
StatePublished - Jan 2013

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Migraine Disorders
Cross-Sectional Studies
Costs and Cost Analysis
Headache
Confidence Intervals
Economic Inflation
Censuses
Longitudinal Studies

Keywords

  • absenteeism
  • chronic migraine
  • cost
  • episodic migraine
  • lost productive time
  • migraine
  • presenteeism

ASJC Scopus subject areas

  • Health Policy
  • Public Health, Environmental and Occupational Health

Cite this

Cost and predictors of lost productive time in chronic migraine and episodic migraine : Results from the American Migraine Prevalence and Prevention (AMPP) Study. / Serrano, Daniel; Manack, Aubrey N.; Reed, Michael L.; Buse, Dawn C.; Varon, Sepideh F.; Lipton, Richard B.

In: Value in Health, Vol. 16, No. 1, 01.2013, p. 31-38.

Research output: Contribution to journalArticle

Serrano, Daniel ; Manack, Aubrey N. ; Reed, Michael L. ; Buse, Dawn C. ; Varon, Sepideh F. ; Lipton, Richard B. / Cost and predictors of lost productive time in chronic migraine and episodic migraine : Results from the American Migraine Prevalence and Prevention (AMPP) Study. In: Value in Health. 2013 ; Vol. 16, No. 1. pp. 31-38.
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