Corynebacterium kroppenstedtii: A challenging culprit in breast abscesses and granulomatous mastitis

Nidhi Saraiya, Marilou Corpuz

Research output: Contribution to journalReview article

2 Scopus citations

Abstract

Purpose of reviewCorynebacterium kroppenstedtii is a difficult pathogen associated with granulomatous mastitis and recurrent breast abscesses. Despite over a dozen studies, there is no guidance on surgical interventions, steroid use, or dosing or duration of antibiotic treatment.Recent findingsInitially seen in predominantly Maori and Pacific Islander multiparous, postlactating women, C. kroppenstedtii breast infection has since been reported throughout the world, including in nulliparous women. Additionally, emerging data suggest that hyperprolactinemia is a modifiable risk factor for these infections. This article reviews a patient case and data from 87 other cases to compile current best practices for diagnosis, treatment, and monitoring, and provides areas for future study.SummaryIn cases of granulomatous mastitis and breast abscess, especially if recurrent, infection with C. kroppenstedtii should be considered. Microbiologists should be alerted to the specialized growth conditions and tools needed for appropriate culturing, identification, and antibiotic susceptibility testing. Clinicians should utilize a multimodal approach with surgical and antibiotic treatment to maximize clinical cure and reduce recurrence.

Original languageEnglish (US)
Pages (from-to)325-332
Number of pages8
JournalCurrent Opinion in Obstetrics and Gynecology
Volume31
Issue number5
DOIs
StatePublished - Oct 1 2019

Keywords

  • breast abscess
  • Corynebacterium kroppenstedtii
  • granulomatous mastitis

ASJC Scopus subject areas

  • Obstetrics and Gynecology

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