TY - JOUR
T1 - Correlations and brain states
T2 - from electrophysiology to functional imaging
AU - Kohn, Adam
AU - Zandvakili, Amin
AU - Smith, Matthew A.
N1 - Funding Information:
We thank Wyeth Bair, Jaime de la Rocha, Peter Latham, and Alfonso Renart for helpful comments on an earlier version of this manuscript. This work was supported in part by a grant from the National Eye Institute EY016774 (AK) and EY018894 (MAS).
PY - 2009/8
Y1 - 2009/8
N2 - Neural activity in cortex is correlated, an observation that has traditionally been attributed to neurons receiving input from a shared and limited presynaptic pool. Recent studies have shown that correlations are also strongly influenced by network fluctuations that operate over a range of spatial and temporal scales, extending in some cases across cortical areas. These fluctuations are sensitive to internal states and external drive, so that correlations themselves depend strongly on cognitive state and stimulus properties. Given the potential impact on population coding, this modulation of correlations may play an important role in sensory processing.
AB - Neural activity in cortex is correlated, an observation that has traditionally been attributed to neurons receiving input from a shared and limited presynaptic pool. Recent studies have shown that correlations are also strongly influenced by network fluctuations that operate over a range of spatial and temporal scales, extending in some cases across cortical areas. These fluctuations are sensitive to internal states and external drive, so that correlations themselves depend strongly on cognitive state and stimulus properties. Given the potential impact on population coding, this modulation of correlations may play an important role in sensory processing.
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U2 - 10.1016/j.conb.2009.06.007
DO - 10.1016/j.conb.2009.06.007
M3 - Review article
C2 - 19608406
AN - SCOPUS:69449095354
SN - 0959-4388
VL - 19
SP - 434
EP - 438
JO - Current Opinion in Neurobiology
JF - Current Opinion in Neurobiology
IS - 4
ER -