Correlation between serum and plasma antibody titers to mycobacterial antigens

Michael Siev, Xian Yu, Rafael Prados-Rosales, Frank T. Martiniuk, Arturo Casadevall, Jacqueline M. Achkar

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

The ability to utilize serum or plasma samples interchangeably is useful for tuberculosis (TB) serology. We demonstrate a strong correlation between antibody titers to several mycobacterial antigens in serum versus plasma from HIV-infected and non-HIV-infected TB and non-TB patients (r = 0.99 to 0.89; P < 0.0001). Plasma and serum can be used interchangeably in the same antibody detection assays.

Original languageEnglish (US)
Pages (from-to)173-175
Number of pages3
JournalClinical and Vaccine Immunology
Volume18
Issue number1
DOIs
StatePublished - Jan 2011

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Plasmas
Antigens
Antibodies
Tuberculosis
Serum
Serology
Assays
HIV

ASJC Scopus subject areas

  • Clinical Biochemistry
  • Immunology
  • Immunology and Allergy
  • Microbiology (medical)

Cite this

Correlation between serum and plasma antibody titers to mycobacterial antigens. / Siev, Michael; Yu, Xian; Prados-Rosales, Rafael; Martiniuk, Frank T.; Casadevall, Arturo; Achkar, Jacqueline M.

In: Clinical and Vaccine Immunology, Vol. 18, No. 1, 01.2011, p. 173-175.

Research output: Contribution to journalArticle

Siev, Michael ; Yu, Xian ; Prados-Rosales, Rafael ; Martiniuk, Frank T. ; Casadevall, Arturo ; Achkar, Jacqueline M. / Correlation between serum and plasma antibody titers to mycobacterial antigens. In: Clinical and Vaccine Immunology. 2011 ; Vol. 18, No. 1. pp. 173-175.
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