Correlation between serum and plasma antibody titers to mycobacterial antigens

Michael Siev, Xian Yu, Rafael Prados-Rosales, Frank T. Martiniuk, Arturo Casadevall, Jacqueline M. Achkar

Research output: Contribution to journalArticle

19 Scopus citations

Abstract

The ability to utilize serum or plasma samples interchangeably is useful for tuberculosis (TB) serology. We demonstrate a strong correlation between antibody titers to several mycobacterial antigens in serum versus plasma from HIV-infected and non-HIV-infected TB and non-TB patients (r = 0.99 to 0.89; P < 0.0001). Plasma and serum can be used interchangeably in the same antibody detection assays.

Original languageEnglish (US)
Pages (from-to)173-175
Number of pages3
JournalClinical and Vaccine Immunology
Volume18
Issue number1
DOIs
StatePublished - Jan 2011

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology
  • Clinical Biochemistry
  • Microbiology (medical)

Fingerprint Dive into the research topics of 'Correlation between serum and plasma antibody titers to mycobacterial antigens'. Together they form a unique fingerprint.

  • Cite this