Controlling the direction of division

Peter Satir

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Quyn and colleagues report that gut stem cells have a biased spindle orientation and asymmetric retention of label-retaining DNA. These features are lost in mouse and human tissues when the microtubule binding protein Apc is mutated. In the developing kidney, Apc acts downstream from primary cilium signaling to influence spindle orientation when noncanonical Wnt signaling predominates. Do gut stem cells also have primary cilia?.

Original languageEnglish (US)
Article number21
JournalStem Cell Research and Therapy
Volume1
Issue number3
DOIs
StatePublished - 2010

Fingerprint

Cilia
Stem cells
Stem Cells
Microtubule Proteins
Labels
Carrier Proteins
Tissue
Kidney
DNA
Direction compound

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology (miscellaneous)
  • Molecular Medicine
  • Cell Biology
  • Medicine (miscellaneous)

Cite this

Controlling the direction of division. / Satir, Peter.

In: Stem Cell Research and Therapy, Vol. 1, No. 3, 21, 2010.

Research output: Contribution to journalArticle

Satir, Peter. / Controlling the direction of division. In: Stem Cell Research and Therapy. 2010 ; Vol. 1, No. 3.
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