TY - JOUR
T1 - Consumption of alcohol, nicotine, and caffeine among depressed outpatients
T2 - Relationship with response to treatment
AU - Worthington, John
AU - Fava, Maurizio
AU - Agustin, Christina
AU - Alpert, Jonathan
AU - Nierenberg, Andrew A.
AU - Pava, Joel A.
AU - Rosenbaum, Jerrold F.
N1 - Funding Information:
This study was partially supported by a grant from the National Institute of Mental Health (NIMH): RO-l NIMH Grant No. MH-48483-03.
PY - 1996
Y1 - 1996
N2 - The authors present findings, from the first investigation of the use of alcohol, nicotine, and caffeine in nonsubstance-abusing outpatients with major depressive disorder The patients (N = 94) were assessed for their intake of alcohol, nicotine, and caffeine, and then treated openly for 8 weeks with 20 mg/day of fluoxetine. The degree of alcohol consumption at baseline was a significant predictor of poorer response to the antidepressant. This relationship remained significant even after adjusting for severity of depression at baseline. Even moderate levels of alcohol consumption appear to negatively affect pharmacologic treatment in depressed outpatients.
AB - The authors present findings, from the first investigation of the use of alcohol, nicotine, and caffeine in nonsubstance-abusing outpatients with major depressive disorder The patients (N = 94) were assessed for their intake of alcohol, nicotine, and caffeine, and then treated openly for 8 weeks with 20 mg/day of fluoxetine. The degree of alcohol consumption at baseline was a significant predictor of poorer response to the antidepressant. This relationship remained significant even after adjusting for severity of depression at baseline. Even moderate levels of alcohol consumption appear to negatively affect pharmacologic treatment in depressed outpatients.
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U2 - 10.1016/S0033-3182(96)71515-3
DO - 10.1016/S0033-3182(96)71515-3
M3 - Article
C2 - 8942202
AN - SCOPUS:0029861148
SN - 0033-3182
VL - 37
SP - 518
EP - 522
JO - Psychosomatics
JF - Psychosomatics
IS - 6
ER -