Consensus on Shared Measures of Mobility and Cognition

From the Canadian Consortium on Neurodegeneration in Aging (CCNA)

Canadian Gait and Cognition Network

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

BACKGROUND: A new paradigm is emerging in which mobility and cognitive impairments, previously studied, diagnosed, and managed separately in older adults, are in fact regulated by shared brain resources. Deterioration in these shared brain mechanisms by normal aging and neurodegeneration increases the risk of developing dementia, falls, and fractures. This new paradigm requires an integrated approach to measuring both domains. We aim to identify a complementary battery of existing tests of mobility and cognition in community-dwelling older adults that enable assessment of motor-cognitive interactions. METHODS: Experts on mobility and cognition in aging participated in a semistructured consensus based on the Delphi process. After performing a scoping review to select candidate tests, multiple rounds of consultations provided structured feedback on tests that captured shared characteristics of mobility and cognition. These tests needed to be sensitive to changes in both mobility and cognition, applicable across research studies and clinics, sensitive to interventions, feasible to perform in older adults, been previously validated, and have minimal ceiling/floor effects. RESULTS: From 17 tests appraised, 10 tests fulfilled prespecified criteria and were selected as part of the "Core-battery" of tests. The expert panel also recommended a "Minimum-battery" of tests that included gait speed, dual-task gait speed, the Montreal Cognitive Assessment and Trail Making Test A&B. CONCLUSIONS: A standardized assessment battery that captures shared characteristics of mobility and cognition seen in aging and neurodegeneration may increase comparability across research studies, detection of subtle or common reversible factors, and accelerate research progress in dementia, falls, and aging-related disabilities.

Original languageEnglish (US)
Pages (from-to)897-909
Number of pages13
JournalThe journals of gerontology. Series A, Biological sciences and medical sciences
Volume74
Issue number6
DOIs
StatePublished - May 16 2019

Fingerprint

Cognition
Consensus
Dementia
Research
Trail Making Test
Independent Living
Brain
Referral and Consultation
Walking Speed

Keywords

  • Aging
  • Cognition
  • Consensus
  • Falls
  • Gait
  • Mobility
  • Neurodegenerative diseases

ASJC Scopus subject areas

  • Aging
  • Geriatrics and Gerontology

Cite this

Consensus on Shared Measures of Mobility and Cognition : From the Canadian Consortium on Neurodegeneration in Aging (CCNA). / Canadian Gait and Cognition Network.

In: The journals of gerontology. Series A, Biological sciences and medical sciences, Vol. 74, No. 6, 16.05.2019, p. 897-909.

Research output: Contribution to journalArticle

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title = "Consensus on Shared Measures of Mobility and Cognition: From the Canadian Consortium on Neurodegeneration in Aging (CCNA)",
abstract = "BACKGROUND: A new paradigm is emerging in which mobility and cognitive impairments, previously studied, diagnosed, and managed separately in older adults, are in fact regulated by shared brain resources. Deterioration in these shared brain mechanisms by normal aging and neurodegeneration increases the risk of developing dementia, falls, and fractures. This new paradigm requires an integrated approach to measuring both domains. We aim to identify a complementary battery of existing tests of mobility and cognition in community-dwelling older adults that enable assessment of motor-cognitive interactions. METHODS: Experts on mobility and cognition in aging participated in a semistructured consensus based on the Delphi process. After performing a scoping review to select candidate tests, multiple rounds of consultations provided structured feedback on tests that captured shared characteristics of mobility and cognition. These tests needed to be sensitive to changes in both mobility and cognition, applicable across research studies and clinics, sensitive to interventions, feasible to perform in older adults, been previously validated, and have minimal ceiling/floor effects. RESULTS: From 17 tests appraised, 10 tests fulfilled prespecified criteria and were selected as part of the {"}Core-battery{"} of tests. The expert panel also recommended a {"}Minimum-battery{"} of tests that included gait speed, dual-task gait speed, the Montreal Cognitive Assessment and Trail Making Test A&B. CONCLUSIONS: A standardized assessment battery that captures shared characteristics of mobility and cognition seen in aging and neurodegeneration may increase comparability across research studies, detection of subtle or common reversible factors, and accelerate research progress in dementia, falls, and aging-related disabilities.",
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author = "{Canadian Gait and Cognition Network} and Manuel Montero-Odasso and Almeida, {Quincy J.} and Louis Bherer and Burhan, {Amer M.} and Richard Camicioli and Julien Doyon and Sarah Fraser and Susan Muir-Hunter and Li, {Karen Z.H.} and Teresa Liu-Ambrose and William McIlroy and Laura Middleton and Morais, {Jos{\'e} A.} and Ryota Sakurai and Mark Speechley and Akshya Vasudev and Olivier Beauchet and Hausdorff, {Jeffrey M.} and Caterina Rosano and Stephanie Studenski and Joe Verghese",
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AU - Montero-Odasso, Manuel

AU - Almeida, Quincy J.

AU - Bherer, Louis

AU - Burhan, Amer M.

AU - Camicioli, Richard

AU - Doyon, Julien

AU - Fraser, Sarah

AU - Muir-Hunter, Susan

AU - Li, Karen Z.H.

AU - Liu-Ambrose, Teresa

AU - McIlroy, William

AU - Middleton, Laura

AU - Morais, José A.

AU - Sakurai, Ryota

AU - Speechley, Mark

AU - Vasudev, Akshya

AU - Beauchet, Olivier

AU - Hausdorff, Jeffrey M.

AU - Rosano, Caterina

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