Congenital heart disease in Down's syndrome patients: A decade of surgical experience

F. A. Baciewicz, W. S. Melvin, D. Basilius, J. T. Davis

Research output: Contribution to journalArticlepeer-review

16 Scopus citations

Abstract

Patients with Down's syndrome represent a significant subset of patients with congenital heart disease. Fifty-five patients with Down's syndrome have undergone surgical treatment for congenital heart disease at our institution in the past decade. Twenty-six had atrioventricular canal, 11 had ventricular septal defect, 7 had secundum atrial septal defect, 7 had tetralogy of Fallot, 3 had primum atrial septal defect and 1 patient had double outlet right ventricle. The thirty day mortality following operative intervention was 16.4%. Mortality was highest for tetralogy of Fallot followed by atrioventricular canal and ventricular septal defect. Long term mortality for all lesions was 27.3% over our follow-up period which averaged 33 months. Thirty day mortality compared similarly to previous reports of surgically treated Down's syndrome patients. When compared to our patients without Down's syndrome, the Down's syndrome population did not exhibit an increased risk for surgical treatment of congenital heart disease.

Original languageEnglish (US)
Pages (from-to)369-371
Number of pages3
JournalThoracic and Cardiovascular Surgeon
Volume37
Issue number6
DOIs
StatePublished - Jan 1 1989
Externally publishedYes

Keywords

  • Congenital heart disease
  • Down's syndrome

ASJC Scopus subject areas

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine

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