Conformational dynamics in human purine nucleoside phosphorylase with reactants and transition-state analogues

Physics & Astronomy

• nucleosides 82%
• purines 80%
• inhibitors 51%
• analogs 42%
• ligands 17%
• phosphates 17%
• proteins 14%
• molecular dynamics 12%
• water 10%
• interactions 7%
• simulation 6%
• molecules 4%

Engineering & Materials Science

• Nucleosides 100%
• Substrates 37%
• Ligands 35%
• Phosphates 30%
• Molecular dynamics 29%
• Proteins 24%
• Computer simulation 14%
• Water 14%
• Molecules 12%

Chemical Compounds

• Purine Nucleoside 68%
• Inosine 66%
• Immucillin H 25%
• Molecular Dynamics 19%
• Phosphate 17%
• Simulation 16%
• Purine 13%
• Ligand 11%
• Transition State 10%
• Solvent 6%
• Reduction 6%
• Protein 5%
• Molecule 4%