Concomitant valve procedures in patients undergoing continuous-flow left ventricular assist device implantation: A single-center experience

Tadahisa Sugiura, Chitaru Kurihara, Masashi Kawabori, Andre C. Critsinelis, Suwei Wang, Andrew B. Civitello, Todd K. Rosengart, O. H. Frazier, Jeffrey A. Morgan

Research output: Contribution to journalArticle

5 Scopus citations

Abstract

Objective: Long-term support with continuous-flow left ventricular assist devices (CF-LVADs) has improved the outcomes of patients with end-stage heart failure. However, valve disease management in patients who undergo CF-LVAD implantation remains controversial. The aim of this study was to assess our single-center experience with patients who underwent a concomitant valve procedure during implantation of a CF-LVAD. Methods: From November 2003 through March 2016, 526 patients underwent primary CF-LVAD implantation with a HeartMate II (St Jude Inc, St Paul, Minn; n = 403) or HeartWare (Medtronic, Minneapolis, Minn; n = 123) device at our center. Of those, 91 underwent a concomitant valve procedure during implantation (CF-LVAD+valve procedure group), whereas 435 did not (CF-LVAD–only group). We compared preoperative characteristics and short-term and mid-term survival rates between these groups. Results: The concomitant valve procedures performed included 13 tricuspid valve repairs, 19 aortic valve repairs or replacements, 30 mitral valve repairs or replacements, and 29 double valve repairs or replacements. Survival rates at 1 month, 6 months, 12 months, and 24 months were 90.3%, 81.4%, 74.9%, and 67.4%, respectively, for the CF-LVAD–only group and 89.0%, 75.8%, 70.3%, and 65.9%, respectively, for the CF-LVAD+valve procedure group (P = .55). The results of Cox regression multivariable modeling showed that performing a concomitant valve procedure was not an independent predictor of mortality (hazard ratio, 1.29; 95% confidence interval, 0.96-1.74; P = .08). Conclusions: In our experience, performing a concomitant valve procedure during CF-LVAD implantation was not associated with an increased mortality rate. The decision to perform a concomitant valve procedure should be made primarily on the basis of clinical indications for the procedure.

Original languageEnglish (US)
Pages (from-to)1083-1089.e1
JournalJournal of Thoracic and Cardiovascular Surgery
Volume158
Issue number4
DOIs
StatePublished - Oct 2019
Externally publishedYes

Keywords

  • concomitant valve procedures
  • heart failure
  • left ventricular assist device
  • valve disease

ASJC Scopus subject areas

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine

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    Sugiura, T., Kurihara, C., Kawabori, M., Critsinelis, A. C., Wang, S., Civitello, A. B., Rosengart, T. K., Frazier, O. H., & Morgan, J. A. (2019). Concomitant valve procedures in patients undergoing continuous-flow left ventricular assist device implantation: A single-center experience. Journal of Thoracic and Cardiovascular Surgery, 158(4), 1083-1089.e1. https://doi.org/10.1016/j.jtcvs.2019.02.040