Computer-assisted static/dynamic renal imaging

A screening test for renovascular hypertension?

H. J. Keim, P. M. Johnson, E. D. Vaughan, K. Beg, D. A. Follett, Leonard M. Freeman, J. H. Laragh

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Computer-assisted static/dynamic renal imaging with [ 197Hg] chlormerodrin and [ 99mTc]pertechnetate was evaluated prospectively as a screening test for renovascular hypertension. Results are reported for 51 patients: 33 with benign essential hypertension and 18 with renovascular hypertension, and for 21 normal controls. All patients underwent renal arteriography. Patients with significant obesity, renal insufficiency, or renoparenchymal disease were excluded from this study. Independent visual analyses of renal gamma images and time-activity transit curves identified 17 of the 18 patients with renovascular hypertension; one study was equivocal. There were five equivocal and three false-positive results in the essential hypertension and normal control groups. The sensitivity of the method was 94% and the specificity 85%. Since the prevalence of the renovascular subset of hypertension is approximately 5%, the predictive value is only 25%. Inclusion of computer-generated data did not improve this result. Accordingly, this method is not recommended as a primary screening test for renovascular hypertension.

Original languageEnglish (US)
Pages (from-to)11-17
Number of pages7
JournalJournal of Nuclear Medicine
Volume20
Issue number1
StatePublished - 1979
Externally publishedYes

Fingerprint

Renovascular Hypertension
Kidney
Chlormerodrin
Sodium Pertechnetate Tc 99m
Renal Insufficiency
Angiography
Obesity
Control Groups

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology

Cite this

Keim, H. J., Johnson, P. M., Vaughan, E. D., Beg, K., Follett, D. A., Freeman, L. M., & Laragh, J. H. (1979). Computer-assisted static/dynamic renal imaging: A screening test for renovascular hypertension? Journal of Nuclear Medicine, 20(1), 11-17.

Computer-assisted static/dynamic renal imaging : A screening test for renovascular hypertension? / Keim, H. J.; Johnson, P. M.; Vaughan, E. D.; Beg, K.; Follett, D. A.; Freeman, Leonard M.; Laragh, J. H.

In: Journal of Nuclear Medicine, Vol. 20, No. 1, 1979, p. 11-17.

Research output: Contribution to journalArticle

Keim, HJ, Johnson, PM, Vaughan, ED, Beg, K, Follett, DA, Freeman, LM & Laragh, JH 1979, 'Computer-assisted static/dynamic renal imaging: A screening test for renovascular hypertension?', Journal of Nuclear Medicine, vol. 20, no. 1, pp. 11-17.
Keim, H. J. ; Johnson, P. M. ; Vaughan, E. D. ; Beg, K. ; Follett, D. A. ; Freeman, Leonard M. ; Laragh, J. H. / Computer-assisted static/dynamic renal imaging : A screening test for renovascular hypertension?. In: Journal of Nuclear Medicine. 1979 ; Vol. 20, No. 1. pp. 11-17.
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