Computed Tomography of the Brain in the Smith-Lemli-Opitz Syndrome

Robert W. Marion; Luis A. Alvarez; Zvi S. Marans; George Lantos; David Chitayat

doi:10.1177/088307388700200305

Computed Tomography of the Brain in the Smith-Lemli-Opitz Syndrome

Robert W. Marion, Luis A. Alvarez, Zvi S. Marans, George Lantos, David Chitayat

Pediatrics

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Abstract

Computed tomographic (CT) scans of the brain in a child with Smith-Lemli-Opitz syndrome revealed enlargement of the ventricular system, hypoplasia of the cerebellum, and abnormal thickening of the gray matter, consistent with pachygyria. These findings have been previously noted in autopsies performed on patients with this disorder. We conclude that CT scanning is a valuable tool in the evaluation of children suspected of having the Smith-Lemli-Opitz syndrome. (J Child Neurol 1987;2:198-200).

Original language	English (US)
Pages (from-to)	198-200
Number of pages	3
Journal	Journal of child neurology
Volume	2
Issue number	3
DOIs	https://doi.org/10.1177/088307388700200305
State	Published - Jul 1987

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Clinical Neurology

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title = "Computed Tomography of the Brain in the Smith-Lemli-Opitz Syndrome",

abstract = "Computed tomographic (CT) scans of the brain in a child with Smith-Lemli-Opitz syndrome revealed enlargement of the ventricular system, hypoplasia of the cerebellum, and abnormal thickening of the gray matter, consistent with pachygyria. These findings have been previously noted in autopsies performed on patients with this disorder. We conclude that CT scanning is a valuable tool in the evaluation of children suspected of having the Smith-Lemli-Opitz syndrome. (J Child Neurol 1987;2:198-200).",

author = "Marion, {Robert W.} and Alvarez, {Luis A.} and Marans, {Zvi S.} and George Lantos and David Chitayat",

year = "1987",

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AU - Marion, Robert W.

AU - Alvarez, Luis A.

AU - Marans, Zvi S.

AU - Lantos, George

AU - Chitayat, David

PY - 1987/7

Y1 - 1987/7

N2 - Computed tomographic (CT) scans of the brain in a child with Smith-Lemli-Opitz syndrome revealed enlargement of the ventricular system, hypoplasia of the cerebellum, and abnormal thickening of the gray matter, consistent with pachygyria. These findings have been previously noted in autopsies performed on patients with this disorder. We conclude that CT scanning is a valuable tool in the evaluation of children suspected of having the Smith-Lemli-Opitz syndrome. (J Child Neurol 1987;2:198-200).

AB - Computed tomographic (CT) scans of the brain in a child with Smith-Lemli-Opitz syndrome revealed enlargement of the ventricular system, hypoplasia of the cerebellum, and abnormal thickening of the gray matter, consistent with pachygyria. These findings have been previously noted in autopsies performed on patients with this disorder. We conclude that CT scanning is a valuable tool in the evaluation of children suspected of having the Smith-Lemli-Opitz syndrome. (J Child Neurol 1987;2:198-200).

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Computed Tomography of the Brain in the Smith-Lemli-Opitz Syndrome

Abstract

ASJC Scopus subject areas

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