Complications of HIV infection: A systems-based approach

Carolyn Chu, Peter A. Selwyn

Research output: Contribution to journalArticle

16 Scopus citations

Abstract

Patients with human immunodefciency virus (HIV) infection often develop multiple complications and comorbidities. Opportunistic infections should always be considered in the evaluation of symptomatic patients with advanced HIV/AIDS, although the overall incidence of these infections has decreased. Primary care of HIV infection includes the early detection of some complications through screening at-risk and symptomatic patients with routine laboratory monitoring (e.g., comprehensive metabolic and lipid panels) and validated tools (e.g., the HIV Dementia Scale). Treatment of many chronic complications is similar for patients with HIV infection and those without infection; however, combination antiretroviral therapy has shown beneft for some conditions, such as HIV-associated nephropathy. For other complications, such as cardiovascular disease and lipoatrophy, management may include switching antiretroviral regimens to reduce exposure to HIV medications known to cause toxicity.

Original languageEnglish (US)
Pages (from-to)395-406
Number of pages12
JournalAmerican family physician
Volume83
Issue number4
Publication statusPublished - Feb 15 2011

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ASJC Scopus subject areas

  • Family Practice

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