Complete sequence of a blakpc-2-harboring incfiik1 plasmid from a klebsiella pneumoniae sequence type 258 strain

Liang Chen, Kalyan D. Chavda, Roberto G. Melano, Michael R. Jacobs, Michael H. Levi, Robert A. Bonomo, Barry N. Kreiswirth

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34 Scopus citations

Abstract

We report the nucleotide sequence of a novel blaKPC-2-harboring IncFIIK1 plasmid, pBK32179, isolated from a carbapenem-resistant Klebsiella pneumoniae ST258 strain from a New York City patient. pBK32179 is 165 kb long, consists of a large backbone of pKPN3-like plasmid, and carries an 18.5-kb blaKPC-2-containing element that is highly similar to plasmid pKpQIL. pBK32179- like plasmids were identified in 8.3% of strains in a collection of 96 K. pneumoniae isolates from hospitals in the New York City area.

Original languageEnglish (US)
Pages (from-to)1542-1545
Number of pages4
JournalAntimicrobial Agents and Chemotherapy
Volume57
Issue number3
DOIs
Publication statusPublished - Mar 1 2013

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ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases

Cite this

Chen, L., Chavda, K. D., Melano, R. G., Jacobs, M. R., Levi, M. H., Bonomo, R. A., & Kreiswirth, B. N. (2013). Complete sequence of a blakpc-2-harboring incfiik1 plasmid from a klebsiella pneumoniae sequence type 258 strain. Antimicrobial Agents and Chemotherapy, 57(3), 1542-1545. https://doi.org/10.1128/AAC.02332-12