Complete sequence of a blakpc-2-harboring incfiik1 plasmid from a klebsiella pneumoniae sequence type 258 strain

Liang Chen, Kalyan D. Chavda, Roberto G. Melano, Michael R. Jacobs, Michael H. Levi, Robert A. Bonomo, Barry N. Kreiswirth

Research output: Contribution to journalArticle

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Abstract

We report the nucleotide sequence of a novel blaKPC-2-harboring IncFIIK1 plasmid, pBK32179, isolated from a carbapenem-resistant Klebsiella pneumoniae ST258 strain from a New York City patient. pBK32179 is 165 kb long, consists of a large backbone of pKPN3-like plasmid, and carries an 18.5-kb blaKPC-2-containing element that is highly similar to plasmid pKpQIL. pBK32179- like plasmids were identified in 8.3% of strains in a collection of 96 K. pneumoniae isolates from hospitals in the New York City area.

Original languageEnglish (US)
Pages (from-to)1542-1545
Number of pages4
JournalAntimicrobial Agents and Chemotherapy
Volume57
Issue number3
DOIs
StatePublished - Mar 2013

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Klebsiella pneumoniae
Plasmids
Carbapenems

ASJC Scopus subject areas

  • Pharmacology (medical)
  • Pharmacology
  • Infectious Diseases

Cite this

Chen, L., Chavda, K. D., Melano, R. G., Jacobs, M. R., Levi, M. H., Bonomo, R. A., & Kreiswirth, B. N. (2013). Complete sequence of a blakpc-2-harboring incfiik1 plasmid from a klebsiella pneumoniae sequence type 258 strain. Antimicrobial Agents and Chemotherapy, 57(3), 1542-1545. https://doi.org/10.1128/AAC.02332-12

Complete sequence of a blakpc-2-harboring incfiik1 plasmid from a klebsiella pneumoniae sequence type 258 strain. / Chen, Liang; Chavda, Kalyan D.; Melano, Roberto G.; Jacobs, Michael R.; Levi, Michael H.; Bonomo, Robert A.; Kreiswirth, Barry N.

In: Antimicrobial Agents and Chemotherapy, Vol. 57, No. 3, 03.2013, p. 1542-1545.

Research output: Contribution to journalArticle

Chen, L, Chavda, KD, Melano, RG, Jacobs, MR, Levi, MH, Bonomo, RA & Kreiswirth, BN 2013, 'Complete sequence of a blakpc-2-harboring incfiik1 plasmid from a klebsiella pneumoniae sequence type 258 strain', Antimicrobial Agents and Chemotherapy, vol. 57, no. 3, pp. 1542-1545. https://doi.org/10.1128/AAC.02332-12
Chen, Liang ; Chavda, Kalyan D. ; Melano, Roberto G. ; Jacobs, Michael R. ; Levi, Michael H. ; Bonomo, Robert A. ; Kreiswirth, Barry N. / Complete sequence of a blakpc-2-harboring incfiik1 plasmid from a klebsiella pneumoniae sequence type 258 strain. In: Antimicrobial Agents and Chemotherapy. 2013 ; Vol. 57, No. 3. pp. 1542-1545.
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