Compartmental organization of calretinin in the rat striatum

Noboru Hiroi

Research output: Contribution to journalArticle

21 Scopus citations

Abstract

The present study examined the compartmental distribution of a calcium-binding protein, calretinin, in the rat striatum. Calretinin-immunoreactive cells were homogeneously scattered throughout the striatum, but calretinin-immunoreactive fibers were clustered as patches in the medial, central and ventral caudoputamen and in the lateral nucleus accumbens. These patches corresponded to striosomes, identified by immunostaining for calbindin-D28 K in adjacent sections. In the medial nucleus accumbens, calretinin-immunoreactive fibers showed diffuse distribution with occasional islands of calretinin-poor zones. These islands contained tightly packed, Nissl-stained cells, which have been previously shown to correspond to μ-opiate receptor-rich patches. Calretinin-positive fibers fill striosomes/patches in the caudoputamen and in the lateral nucleus accumbens and avoid them in the medial nucleus accumbens.

Original languageEnglish (US)
Pages (from-to)223-226
Number of pages4
JournalNeuroscience Letters
Volume197
Issue number3
DOIs
Publication statusPublished - Sep 15 1995

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Keywords

  • Calbindin
  • Calcium-binding protein
  • Calretinin
  • Matrix
  • Patch
  • Striatum
  • Striosome

ASJC Scopus subject areas

  • Neuroscience(all)

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