Comparison of sonograms and liver histologic findings in patients with chronic hepatitis C virus infection

Rosalyn Kutcher, Gail S. Smith, Filiz Sen, Scott F. Gelman, Sumi Mitsudo, Swan N. Thung, John F. Reinus

Research output: Contribution to journalArticle

31 Citations (Scopus)

Abstract

Gray scale ultrasonographic images of the liver were correlated with histologic findings in patients with chronic hepatitis C virus infection. The gray scale patterns of 64 livers with chronic hepatitis C virus infection were categorized as normal, fatty, fibrofatty, fibrotic, or inflammatory and were graded as mild, moderate, or severe. Liver biopsy specimens also were analyzed for the presence of fat, inflammation, and fibrosis and graded similarly. No correlation was found between fatty and fibrofatty sonographic findings with any of the three histologic patterns. Correlations were found between fibrotic sonographic findings and both fibrotic and inflammatory histologic findings (r = 0.27; P = 0.03). Although some pathologic features of liver disease were detected by ultrasonography, no useful correlation was noted between results of sonography and histologic examination.

Original languageEnglish (US)
Pages (from-to)321-325
Number of pages5
JournalJournal of Ultrasound in Medicine
Volume17
Issue number5
StatePublished - May 1998

Fingerprint

hepatitis
sonograms
viruses
infectious diseases
Chronic Hepatitis C
Virus Diseases
liver
Hepacivirus
Liver
gray scale
Ultrasonography
fibrosis
Liver Diseases
fats
Fibrosis
Fats
Inflammation
Biopsy
examination

Keywords

  • Hepatitis C virus
  • Infection, Hepatitic C
  • Liver, Ultrasonography

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology
  • Acoustics and Ultrasonics

Cite this

Kutcher, R., Smith, G. S., Sen, F., Gelman, S. F., Mitsudo, S., Thung, S. N., & Reinus, J. F. (1998). Comparison of sonograms and liver histologic findings in patients with chronic hepatitis C virus infection. Journal of Ultrasound in Medicine, 17(5), 321-325.

Comparison of sonograms and liver histologic findings in patients with chronic hepatitis C virus infection. / Kutcher, Rosalyn; Smith, Gail S.; Sen, Filiz; Gelman, Scott F.; Mitsudo, Sumi; Thung, Swan N.; Reinus, John F.

In: Journal of Ultrasound in Medicine, Vol. 17, No. 5, 05.1998, p. 321-325.

Research output: Contribution to journalArticle

Kutcher, R, Smith, GS, Sen, F, Gelman, SF, Mitsudo, S, Thung, SN & Reinus, JF 1998, 'Comparison of sonograms and liver histologic findings in patients with chronic hepatitis C virus infection', Journal of Ultrasound in Medicine, vol. 17, no. 5, pp. 321-325.
Kutcher R, Smith GS, Sen F, Gelman SF, Mitsudo S, Thung SN et al. Comparison of sonograms and liver histologic findings in patients with chronic hepatitis C virus infection. Journal of Ultrasound in Medicine. 1998 May;17(5):321-325.
Kutcher, Rosalyn ; Smith, Gail S. ; Sen, Filiz ; Gelman, Scott F. ; Mitsudo, Sumi ; Thung, Swan N. ; Reinus, John F. / Comparison of sonograms and liver histologic findings in patients with chronic hepatitis C virus infection. In: Journal of Ultrasound in Medicine. 1998 ; Vol. 17, No. 5. pp. 321-325.
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