Comparison of nifedipine and ritodrine for the treatment of preterm labor

L. A. Bracero, E. Leikin, N. Kirshenbaum, N. Tejani

Research output: Contribution to journalArticle

62 Citations (Scopus)

Abstract

Treatment of preterm labor with beta-sympathomimetics has been questioned because of the many maternal and fetal complications associated with its use. Nifedipine, a calcium antagonist, has been shown to suppress uterine activity in vitro and in vivo. A randomized prospective study was performed to compare the efficacy of nifedipine to ritodrine in the suppression of preterm labor. Data obtained from 42 women, of which 19 were randomized to the ritodrine group and 23 to the nifedipine group, were analyzed. Ritodrine and nifedipine proved to be equally effective in the suppression of preterm labor. However, the nifedipine group had fewer maternal and fetal complications.

Original languageEnglish (US)
Pages (from-to)365-369
Number of pages5
JournalAmerican Journal of Perinatology
Volume8
Issue number6
StatePublished - 1991
Externally publishedYes

Fingerprint

Ritodrine
Premature Obstetric Labor
Nifedipine
Mothers
Therapeutics
Sympathomimetics
Prospective Studies
Calcium

ASJC Scopus subject areas

  • Obstetrics and Gynecology
  • Pediatrics, Perinatology, and Child Health

Cite this

Bracero, L. A., Leikin, E., Kirshenbaum, N., & Tejani, N. (1991). Comparison of nifedipine and ritodrine for the treatment of preterm labor. American Journal of Perinatology, 8(6), 365-369.

Comparison of nifedipine and ritodrine for the treatment of preterm labor. / Bracero, L. A.; Leikin, E.; Kirshenbaum, N.; Tejani, N.

In: American Journal of Perinatology, Vol. 8, No. 6, 1991, p. 365-369.

Research output: Contribution to journalArticle

Bracero, LA, Leikin, E, Kirshenbaum, N & Tejani, N 1991, 'Comparison of nifedipine and ritodrine for the treatment of preterm labor', American Journal of Perinatology, vol. 8, no. 6, pp. 365-369.
Bracero, L. A. ; Leikin, E. ; Kirshenbaum, N. ; Tejani, N. / Comparison of nifedipine and ritodrine for the treatment of preterm labor. In: American Journal of Perinatology. 1991 ; Vol. 8, No. 6. pp. 365-369.
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