Comparison of Nifedipine and Ritodrine for the Treatment of Preterm Labor

Luis A. Bracero, Enid Leikin, Nancy Kirshenbaum, Nergesh Tejani

Research output: Contribution to journalArticle

62 Scopus citations

Abstract

Treatment of preterm labor with beta-sympathomimetics has been questioned because of the many maternal and fetal complications associated with its use. Nifedipine, a calcium antagonist, has been shown to suppress uterine activity in vitro and in vivo. A randomized prospective study was performed to compare the efficacy of nifedipine to ritodrine in the suppression of preterm labor. Data obtained from 42 women, of which 19 were randomized to the ritodrine group and 23 to the nifedipine group, were analyzed. Ritodrine and nifedipine proved to be equally effective in the suppression of preterm labor. However, the nifedipine group had fewer maternal and fetal complications.

Original languageEnglish (US)
Pages (from-to)365-369
Number of pages5
JournalAmerican Journal of Perinatology
Volume8
Issue number6
DOIs
StatePublished - Nov 1991

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynecology

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