Abstract
Treatment of preterm labor with beta-sympathomimetics has been questioned because of the many maternal and fetal complications associated with its use. Nifedipine, a calcium antagonist, has been shown to suppress uterine activity in vitro and in vivo. A randomized prospective study was performed to compare the efficacy of nifedipine to ritodrine in the suppression of preterm labor. Data obtained from 42 women, of which 19 were randomized to the ritodrine group and 23 to the nifedipine group, were analyzed. Ritodrine and nifedipine proved to be equally effective in the suppression of preterm labor. However, the nifedipine group had fewer maternal and fetal complications.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 365-369 |
| Number of pages | 5 |
| Journal | American Journal of Perinatology |
| Volume | 8 |
| Issue number | 6 |
| State | Published - 1991 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Obstetrics and Gynecology
- Pediatrics, Perinatology, and Child Health
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Comparison of nifedipine and ritodrine for the treatment of preterm labor. / Bracero, L. A.; Leikin, E.; Kirshenbaum, N.; Tejani, N.
In: American Journal of Perinatology, Vol. 8, No. 6, 1991, p. 365-369.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Comparison of nifedipine and ritodrine for the treatment of preterm labor
AU - Bracero, L. A.
AU - Leikin, E.
AU - Kirshenbaum, N.
AU - Tejani, N.
PY - 1991
Y1 - 1991
N2 - Treatment of preterm labor with beta-sympathomimetics has been questioned because of the many maternal and fetal complications associated with its use. Nifedipine, a calcium antagonist, has been shown to suppress uterine activity in vitro and in vivo. A randomized prospective study was performed to compare the efficacy of nifedipine to ritodrine in the suppression of preterm labor. Data obtained from 42 women, of which 19 were randomized to the ritodrine group and 23 to the nifedipine group, were analyzed. Ritodrine and nifedipine proved to be equally effective in the suppression of preterm labor. However, the nifedipine group had fewer maternal and fetal complications.
AB - Treatment of preterm labor with beta-sympathomimetics has been questioned because of the many maternal and fetal complications associated with its use. Nifedipine, a calcium antagonist, has been shown to suppress uterine activity in vitro and in vivo. A randomized prospective study was performed to compare the efficacy of nifedipine to ritodrine in the suppression of preterm labor. Data obtained from 42 women, of which 19 were randomized to the ritodrine group and 23 to the nifedipine group, were analyzed. Ritodrine and nifedipine proved to be equally effective in the suppression of preterm labor. However, the nifedipine group had fewer maternal and fetal complications.
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UR - http://www.scopus.com/inward/citedby.url?scp=0026040798&partnerID=8YFLogxK
M3 - Article
C2 - 1814297
AN - SCOPUS:0026040798
VL - 8
SP - 365
EP - 369
JO - American Journal of Perinatology
JF - American Journal of Perinatology
SN - 0735-1631
IS - 6
ER -