Comparative protein structure modelling

András Fiser

doi:10.1007/978-1-4020-9058-5_3

Comparative protein structure modelling

András Fiser

Systems & Computational Biology

Research output: Chapter in Book/Report/Conference proceeding › Chapter

2 Scopus citations

Abstract

A prerequisite to understand cell functioning on the system level is the knowledge of three-dimensional protein structures that mediate biochemical inter actions. The explosion in the number of available gene sequences set the stage for the next step in genome scale projects, to obtain three dimensional structures for each protein. To achieve this ambitious goal, the costly and slow structure determi nation experiments are boosted with theoretical approaches. The current state and recent advances in structure modelling approaches are reviewed here, with special emphasis on comparative structure modelling techniques

Original language	English (US)
Title of host publication	From Protein Structure to Function with Bioinformatics
Publisher	Springer Netherlands
Pages	57-90
Number of pages	34
ISBN (Print)	9781402090578
DOIs	https://doi.org/10.1007/978-1-4020-9058-5_3
State	Published - Dec 1 2009

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)

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