Comparative covalent protein binding of 2,5-Hexanedione and 3-Acetyl-2,5-Hexanedione in the rat

Medicine & Life Sciences

• 3-acetyl-2,5-hexanedione 100%
• 2,5-hexanedione 69%
• Protein Binding 41%
• Pyrroles 39%
• Intermediate Filaments 22%
• Globins 13%
• 2,5-dimethylpyrrole 11%
• Proteins 9%
• n-hexane 7%
• Neurofilament Proteins 7%
• Cytoskeletal Proteins 6%
• Protein Subunits 5%
• Hindlimb 5%
• Sodium Dodecyl Sulfate 5%
• Amines 5%
• Lysine 5%
• Polyacrylamide Gel Electrophoresis 4%
• Blood Proteins 4%
• Wistar Rats 4%
• Body Weight 3%
• Animals 2%

Chemical Compounds

• 2,5-hexanedione 67%
• Protein 17%
• Pyrrole 17%
• Neurotoxic 11%
• Globin 11%
• Neurotoxicity 11%
• Diketone 11%
• Adduct 9%
• Pyrroles 5%
• Lysine 4%
• Reaction Stoichiometry 3%
• Dose 3%
• Metabolite 3%
• Amine 2%
• Plasma 2%
• Weight 2%
• Oxidation Reaction 2%
• Time 1%