Combined psychotherapy and pharmacotherapy for depression. A systematic analysis of the evidence

H. R. Conte, R. Plutchik, K. V. Wild, T. B. Karasu

Research output: Contribution to journalArticle

109 Citations (Scopus)

Abstract

To determine whether combined psychotherapy and pharmacotherapy is superior to alternative therapies for unipolar depression, we reviewed all controlled studies of outpatients treated for unipolar depression reported between 1974 and 1984. To accomplish this, we developed a new statistical approach that is specific in its method of evaluating the quality of each study and specific about the weights given to each outcome. The combined active treatments (drugs plus psychotherapy) were appreciably more effective than the placebo conditions but only slightly superior to psychotherapy alone, pharmacotherapy alone, or either of these combined with a placebo.

Original languageEnglish (US)
Pages (from-to)471-479
Number of pages9
JournalArchives of General Psychiatry
Volume43
Issue number5
StatePublished - 1986

Fingerprint

Psychotherapy
Depression
Depressive Disorder
Drug Therapy
Placebos
Complementary Therapies
Outpatients
Weights and Measures
Pharmaceutical Preparations
Therapeutics

ASJC Scopus subject areas

  • Psychiatry and Mental health

Cite this

Conte, H. R., Plutchik, R., Wild, K. V., & Karasu, T. B. (1986). Combined psychotherapy and pharmacotherapy for depression. A systematic analysis of the evidence. Archives of General Psychiatry, 43(5), 471-479.

Combined psychotherapy and pharmacotherapy for depression. A systematic analysis of the evidence. / Conte, H. R.; Plutchik, R.; Wild, K. V.; Karasu, T. B.

In: Archives of General Psychiatry, Vol. 43, No. 5, 1986, p. 471-479.

Research output: Contribution to journalArticle

Conte, HR, Plutchik, R, Wild, KV & Karasu, TB 1986, 'Combined psychotherapy and pharmacotherapy for depression. A systematic analysis of the evidence', Archives of General Psychiatry, vol. 43, no. 5, pp. 471-479.
Conte, H. R. ; Plutchik, R. ; Wild, K. V. ; Karasu, T. B. / Combined psychotherapy and pharmacotherapy for depression. A systematic analysis of the evidence. In: Archives of General Psychiatry. 1986 ; Vol. 43, No. 5. pp. 471-479.
@article{4b104c93fb3942c2b1000b517c6c5ed3,
title = "Combined psychotherapy and pharmacotherapy for depression. A systematic analysis of the evidence",
abstract = "To determine whether combined psychotherapy and pharmacotherapy is superior to alternative therapies for unipolar depression, we reviewed all controlled studies of outpatients treated for unipolar depression reported between 1974 and 1984. To accomplish this, we developed a new statistical approach that is specific in its method of evaluating the quality of each study and specific about the weights given to each outcome. The combined active treatments (drugs plus psychotherapy) were appreciably more effective than the placebo conditions but only slightly superior to psychotherapy alone, pharmacotherapy alone, or either of these combined with a placebo.",
author = "Conte, {H. R.} and R. Plutchik and Wild, {K. V.} and Karasu, {T. B.}",
year = "1986",
language = "English (US)",
volume = "43",
pages = "471--479",
journal = "JAMA Psychiatry",
issn = "2168-622X",
publisher = "American Medical Association",
number = "5",

}

TY - JOUR

T1 - Combined psychotherapy and pharmacotherapy for depression. A systematic analysis of the evidence

AU - Conte, H. R.

AU - Plutchik, R.

AU - Wild, K. V.

AU - Karasu, T. B.

PY - 1986

Y1 - 1986

N2 - To determine whether combined psychotherapy and pharmacotherapy is superior to alternative therapies for unipolar depression, we reviewed all controlled studies of outpatients treated for unipolar depression reported between 1974 and 1984. To accomplish this, we developed a new statistical approach that is specific in its method of evaluating the quality of each study and specific about the weights given to each outcome. The combined active treatments (drugs plus psychotherapy) were appreciably more effective than the placebo conditions but only slightly superior to psychotherapy alone, pharmacotherapy alone, or either of these combined with a placebo.

AB - To determine whether combined psychotherapy and pharmacotherapy is superior to alternative therapies for unipolar depression, we reviewed all controlled studies of outpatients treated for unipolar depression reported between 1974 and 1984. To accomplish this, we developed a new statistical approach that is specific in its method of evaluating the quality of each study and specific about the weights given to each outcome. The combined active treatments (drugs plus psychotherapy) were appreciably more effective than the placebo conditions but only slightly superior to psychotherapy alone, pharmacotherapy alone, or either of these combined with a placebo.

UR - http://www.scopus.com/inward/record.url?scp=0022529685&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0022529685&partnerID=8YFLogxK

M3 - Article

C2 - 3516110

AN - SCOPUS:0022529685

VL - 43

SP - 471

EP - 479

JO - JAMA Psychiatry

JF - JAMA Psychiatry

SN - 2168-622X

IS - 5

ER -