Combined chemotherapy and radiotherapy in patients with advanced squamous carcinoma of the cervix (cis-platinum-bleomycin-vinblastine)

R. Soeters; B. Bloch; W. Levin; C. M.D. Dehaeck; G. Goldberg

doi:10.1016/0090-8258(89)90600-8

Combined chemotherapy and radiotherapy in patients with advanced squamous carcinoma of the cervix (cis-platinum-bleomycin-vinblastine)

R. Soeters, B. Bloch, W. Levin, C. M.D. Dehaeck, G. Goldberg

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

In a pilot study, nine patients with advanced carcinoma of the cervix were treated with combination chemotherapy including cis-platinum, vinblastine, and bleomycin repeated at 3-week intervals for three courses followed by radiotherapy. Only one patient showed a partial response (reduction of tumor size more than 50%). There were no complete responses. Five of the nine patients have died from the disease with a median survival time of 20 months. These findings suggest that this particular combination of chemotherapy with radiotherapy does not have a significant effect in patients with advanced stage carcinoma of the cervix.

Original language	English (US)
Pages (from-to)	44-45
Number of pages	2
Journal	Gynecologic Oncology
Volume	33
Issue number	1
DOIs	https://doi.org/10.1016/0090-8258(89)90600-8
State	Published - Apr 1989
Externally published	Yes

ASJC Scopus subject areas

Oncology
Obstetrics and Gynecology

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AU - Dehaeck, C. M.D.

AU - Goldberg, G.

PY - 1989/4

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N2 - In a pilot study, nine patients with advanced carcinoma of the cervix were treated with combination chemotherapy including cis-platinum, vinblastine, and bleomycin repeated at 3-week intervals for three courses followed by radiotherapy. Only one patient showed a partial response (reduction of tumor size more than 50%). There were no complete responses. Five of the nine patients have died from the disease with a median survival time of 20 months. These findings suggest that this particular combination of chemotherapy with radiotherapy does not have a significant effect in patients with advanced stage carcinoma of the cervix.

AB - In a pilot study, nine patients with advanced carcinoma of the cervix were treated with combination chemotherapy including cis-platinum, vinblastine, and bleomycin repeated at 3-week intervals for three courses followed by radiotherapy. Only one patient showed a partial response (reduction of tumor size more than 50%). There were no complete responses. Five of the nine patients have died from the disease with a median survival time of 20 months. These findings suggest that this particular combination of chemotherapy with radiotherapy does not have a significant effect in patients with advanced stage carcinoma of the cervix.

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Combined chemotherapy and radiotherapy in patients with advanced squamous carcinoma of the cervix (cis-platinum-bleomycin-vinblastine)

Abstract

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