Cognitive dysfunction in autoimmune rheumatic diseases

Csaba Oláh, Noa Schwartz, Christopher Denton, Zsófia Kardos, Chaim Putterman, Zoltán Szekanecz

Research output: Contribution to journalReview article

Abstract

For people with chronic autoimmune rheumatic diseases (AIRD), such as rheumatoid arthritis (RA), systemic lupus erythematosus (SLE) or systemic sclerosis (SSc), normal cognitive functions are essential for performing daily activities. These diseases may be associated with cognitive dysfunction (CD). In RA, CD has been associated with age, lower education and disease duration and activity. Great advances have been achieved in neuropsychiatric SLE in the identification of pathogenic pathways, assessment and possible treatment strategies. SSc rarely exerts direct effects on the brain and cognitive function. However, the psychological burden that includes depression, anxiety and social impact may be high. AIRD patients with sustained disease activity, organ damage or lower education should be evaluated for CD. The control of systemic inflammation together with tailored behavioural cognitive therapies may benefit these patients.

Original languageEnglish (US)
Article number78
JournalArthritis Research and Therapy
Volume22
Issue number1
DOIs
StatePublished - Apr 15 2020

Keywords

  • Cognitive dysfunction
  • Cognitive function
  • Neuropsychiatric lupus
  • Rheumatoid arthritis
  • Systemic lupus erythematosus
  • Systemic sclerosis

ASJC Scopus subject areas

  • Rheumatology
  • Immunology and Allergy
  • Immunology

Fingerprint Dive into the research topics of 'Cognitive dysfunction in autoimmune rheumatic diseases'. Together they form a unique fingerprint.

  • Cite this