Coal mining is associated with lung cancer risk in Xuanwei, China

Howard D. Hosgood, Robert S. Chapman, Hu Wei, Xingzhou He, Linwei Tian, Larry Z. Liu, Hong Lai, Lawrence S. Engel, Wei Chen, Nathaniel Rothman, Qing Lan

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Background: Xuanwei, China, experiences some of the highest rates of lung cancer in China. While lung cancer risk has been linked to the household use of bituminous coal, no study has comprehensively evaluated the risk of lung cancer associated with the mining of this coal in Xuanwei. In Xuanwei, coal is typically extracted from underground mines, without ventilation, and transported to the surface using carts powered by manpower or electricity. Methods: We evaluated the risk of lung cancer and working as a coal miner, in the absence of diesel exhaust exposure, in a population-based case-control study of 260 male lung cancer cases and 260 age-matched male controls with information on occupational histories. Odds ratios (ORs) and 95% confidence intervals (CIs) for working as a coal miner and years of working as a coal miner were calculated by conditional logistic regression, adjusting for potential confounders, such as smoking and household coal use. Results: We observed an increased risk of lung cancer among coal miners (OR=2.7; 95%CI=1.3-5.6) compared to noncoal miners. Further, a dose-response relationship was observed for the risk of lung cancer and the number of years working as a coal miner (P trend=0.02), with those working as miners for more than 10 years experiencing an almost fourfold increased risk (OR=3.8; 95%CI=1.4-10.3) compared to noncoal miners. Conclusions: These findings suggest that coal mining in Xuanwei may be a risk factor for lung cancer.

Original languageEnglish (US)
Pages (from-to)5-10
Number of pages6
JournalAmerican Journal of Industrial Medicine
Volume55
Issue number1
DOIs
StatePublished - Jan 2012
Externally publishedYes

Fingerprint

Coal Mining
Coal
China
Lung Neoplasms
Odds Ratio
Confidence Intervals
Vehicle Emissions
Electricity
Miners
Ventilation
Case-Control Studies
Logistic Models
Smoking

Keywords

  • China
  • Coal mining
  • Lung cancer
  • Occupation
  • Xuanwei

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health

Cite this

Coal mining is associated with lung cancer risk in Xuanwei, China. / Hosgood, Howard D.; Chapman, Robert S.; Wei, Hu; He, Xingzhou; Tian, Linwei; Liu, Larry Z.; Lai, Hong; Engel, Lawrence S.; Chen, Wei; Rothman, Nathaniel; Lan, Qing.

In: American Journal of Industrial Medicine, Vol. 55, No. 1, 01.2012, p. 5-10.

Research output: Contribution to journalArticle

Hosgood, HD, Chapman, RS, Wei, H, He, X, Tian, L, Liu, LZ, Lai, H, Engel, LS, Chen, W, Rothman, N & Lan, Q 2012, 'Coal mining is associated with lung cancer risk in Xuanwei, China', American Journal of Industrial Medicine, vol. 55, no. 1, pp. 5-10. https://doi.org/10.1002/ajim.21014
Hosgood, Howard D. ; Chapman, Robert S. ; Wei, Hu ; He, Xingzhou ; Tian, Linwei ; Liu, Larry Z. ; Lai, Hong ; Engel, Lawrence S. ; Chen, Wei ; Rothman, Nathaniel ; Lan, Qing. / Coal mining is associated with lung cancer risk in Xuanwei, China. In: American Journal of Industrial Medicine. 2012 ; Vol. 55, No. 1. pp. 5-10.
@article{f2c40a14af41494fbe148c64585995ae,
title = "Coal mining is associated with lung cancer risk in Xuanwei, China",
abstract = "Background: Xuanwei, China, experiences some of the highest rates of lung cancer in China. While lung cancer risk has been linked to the household use of bituminous coal, no study has comprehensively evaluated the risk of lung cancer associated with the mining of this coal in Xuanwei. In Xuanwei, coal is typically extracted from underground mines, without ventilation, and transported to the surface using carts powered by manpower or electricity. Methods: We evaluated the risk of lung cancer and working as a coal miner, in the absence of diesel exhaust exposure, in a population-based case-control study of 260 male lung cancer cases and 260 age-matched male controls with information on occupational histories. Odds ratios (ORs) and 95{\%} confidence intervals (CIs) for working as a coal miner and years of working as a coal miner were calculated by conditional logistic regression, adjusting for potential confounders, such as smoking and household coal use. Results: We observed an increased risk of lung cancer among coal miners (OR=2.7; 95{\%}CI=1.3-5.6) compared to noncoal miners. Further, a dose-response relationship was observed for the risk of lung cancer and the number of years working as a coal miner (P trend=0.02), with those working as miners for more than 10 years experiencing an almost fourfold increased risk (OR=3.8; 95{\%}CI=1.4-10.3) compared to noncoal miners. Conclusions: These findings suggest that coal mining in Xuanwei may be a risk factor for lung cancer.",
keywords = "China, Coal mining, Lung cancer, Occupation, Xuanwei",
author = "Hosgood, {Howard D.} and Chapman, {Robert S.} and Hu Wei and Xingzhou He and Linwei Tian and Liu, {Larry Z.} and Hong Lai and Engel, {Lawrence S.} and Wei Chen and Nathaniel Rothman and Qing Lan",
year = "2012",
month = "1",
doi = "10.1002/ajim.21014",
language = "English (US)",
volume = "55",
pages = "5--10",
journal = "American Journal of Industrial Medicine",
issn = "0271-3586",
publisher = "Wiley-Liss Inc.",
number = "1",

}

TY - JOUR

T1 - Coal mining is associated with lung cancer risk in Xuanwei, China

AU - Hosgood, Howard D.

AU - Chapman, Robert S.

AU - Wei, Hu

AU - He, Xingzhou

AU - Tian, Linwei

AU - Liu, Larry Z.

AU - Lai, Hong

AU - Engel, Lawrence S.

AU - Chen, Wei

AU - Rothman, Nathaniel

AU - Lan, Qing

PY - 2012/1

Y1 - 2012/1

N2 - Background: Xuanwei, China, experiences some of the highest rates of lung cancer in China. While lung cancer risk has been linked to the household use of bituminous coal, no study has comprehensively evaluated the risk of lung cancer associated with the mining of this coal in Xuanwei. In Xuanwei, coal is typically extracted from underground mines, without ventilation, and transported to the surface using carts powered by manpower or electricity. Methods: We evaluated the risk of lung cancer and working as a coal miner, in the absence of diesel exhaust exposure, in a population-based case-control study of 260 male lung cancer cases and 260 age-matched male controls with information on occupational histories. Odds ratios (ORs) and 95% confidence intervals (CIs) for working as a coal miner and years of working as a coal miner were calculated by conditional logistic regression, adjusting for potential confounders, such as smoking and household coal use. Results: We observed an increased risk of lung cancer among coal miners (OR=2.7; 95%CI=1.3-5.6) compared to noncoal miners. Further, a dose-response relationship was observed for the risk of lung cancer and the number of years working as a coal miner (P trend=0.02), with those working as miners for more than 10 years experiencing an almost fourfold increased risk (OR=3.8; 95%CI=1.4-10.3) compared to noncoal miners. Conclusions: These findings suggest that coal mining in Xuanwei may be a risk factor for lung cancer.

AB - Background: Xuanwei, China, experiences some of the highest rates of lung cancer in China. While lung cancer risk has been linked to the household use of bituminous coal, no study has comprehensively evaluated the risk of lung cancer associated with the mining of this coal in Xuanwei. In Xuanwei, coal is typically extracted from underground mines, without ventilation, and transported to the surface using carts powered by manpower or electricity. Methods: We evaluated the risk of lung cancer and working as a coal miner, in the absence of diesel exhaust exposure, in a population-based case-control study of 260 male lung cancer cases and 260 age-matched male controls with information on occupational histories. Odds ratios (ORs) and 95% confidence intervals (CIs) for working as a coal miner and years of working as a coal miner were calculated by conditional logistic regression, adjusting for potential confounders, such as smoking and household coal use. Results: We observed an increased risk of lung cancer among coal miners (OR=2.7; 95%CI=1.3-5.6) compared to noncoal miners. Further, a dose-response relationship was observed for the risk of lung cancer and the number of years working as a coal miner (P trend=0.02), with those working as miners for more than 10 years experiencing an almost fourfold increased risk (OR=3.8; 95%CI=1.4-10.3) compared to noncoal miners. Conclusions: These findings suggest that coal mining in Xuanwei may be a risk factor for lung cancer.

KW - China

KW - Coal mining

KW - Lung cancer

KW - Occupation

KW - Xuanwei

UR - http://www.scopus.com/inward/record.url?scp=83155181504&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=83155181504&partnerID=8YFLogxK

U2 - 10.1002/ajim.21014

DO - 10.1002/ajim.21014

M3 - Article

VL - 55

SP - 5

EP - 10

JO - American Journal of Industrial Medicine

JF - American Journal of Industrial Medicine

SN - 0271-3586

IS - 1

ER -