Closing the loop: Practical and theoretical

C. M. Peterson, L. B. Jovanovic, M. Brownlee, R. L. Jones, A. Cerami

Research output: Contribution to journalArticle

15 Scopus citations

Abstract

Using presently available technologies, a closed-loop system can be devised that employs patient-monitored glucose determinations and self-adjusted insulin administration. Improved glucose control has been documented in type I diabetes and in pregnant women with insulin-dependent diabetes mellitus. In pregnancy, self-administered insulin may achieve levels of carbohydrate control that are superior to those achieved using a self-contained glucose-controlled insulin infusion system, programmed by existing algorithms. Improved closed-loop systems are necessary in order to achieve carbohydrate 'control' that will surpass that which can be attained using presently available means. A potential approach might employ a lectin glucose-controlled insulin delivery system.

Original languageEnglish (US)
Pages (from-to)318-321
Number of pages4
JournalDiabetes care
Volume3
Issue number2
DOIs
StatePublished - Jan 1 1980

ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism
  • Advanced and Specialized Nursing

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    Peterson, C. M., Jovanovic, L. B., Brownlee, M., Jones, R. L., & Cerami, A. (1980). Closing the loop: Practical and theoretical. Diabetes care, 3(2), 318-321. https://doi.org/10.2337/diacare.3.2.318