Clonal growth in vitro by mouse Kupffer cells

Dien Ming Chen, Hsiu San Lin, Philip Stahl, E. Richard Stanley

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Mouse liver Kupffer cells were induced to proliferate and form discrete colonies of mononuclear phagocytes in vitro. These colony-forming cells from the liver are similar to other mononuclear phagocyte colony-forming cells in that they require a colony-stimulating factor present in medium conditioned by L cells for proliferation in vitro. Cells in the colonies were phagocytic and had IgG receptors on the membrane. For this class of colony-forming cells, the D0 value to gamma irradiation in vitro was 108 rads.

Original languageEnglish (US)
Pages (from-to)103-109
Number of pages7
JournalExperimental Cell Research
Volume121
Issue number1
DOIs
StatePublished - 1979

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Kupffer Cells
Phagocytes
Growth
IgG Receptors
Colony-Stimulating Factors
Liver
Conditioned Culture Medium
Cell Proliferation
Membranes
In Vitro Techniques

ASJC Scopus subject areas

  • Cell Biology

Cite this

Chen, D. M., Lin, H. S., Stahl, P., & Stanley, E. R. (1979). Clonal growth in vitro by mouse Kupffer cells. Experimental Cell Research, 121(1), 103-109. https://doi.org/10.1016/0014-4827(79)90449-X

Clonal growth in vitro by mouse Kupffer cells. / Chen, Dien Ming; Lin, Hsiu San; Stahl, Philip; Stanley, E. Richard.

In: Experimental Cell Research, Vol. 121, No. 1, 1979, p. 103-109.

Research output: Contribution to journalArticle

Chen, DM, Lin, HS, Stahl, P & Stanley, ER 1979, 'Clonal growth in vitro by mouse Kupffer cells', Experimental Cell Research, vol. 121, no. 1, pp. 103-109. https://doi.org/10.1016/0014-4827(79)90449-X
Chen, Dien Ming ; Lin, Hsiu San ; Stahl, Philip ; Stanley, E. Richard. / Clonal growth in vitro by mouse Kupffer cells. In: Experimental Cell Research. 1979 ; Vol. 121, No. 1. pp. 103-109.
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