Clonal chromosome aberrations with monosomy of chromosome 8 in a case of grade III chondrosarcoma

Konrad Ptaszynski, K.h. Ramesh, Linda A. Cannizzaro

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

We report cytogenetic findings in a case of grade III chondrosarcoma. Complex clonal chromosome aberrations including monosomy of chromosomes 4, 8, 13, and a consistent t(5;14)(q23;p12) were observed in all cells. There were no structural or numerical anomalies involving chromosome 12. The complexity of the chromosome aberrations reflect the advanced stage of this chondrosarcoma; we suggest a possible involvement of the EXT1 gene located on chromosome 8.

Original languageEnglish (US)
Pages (from-to)60-63
Number of pages4
JournalCancer Genetics and Cytogenetics
Volume97
Issue number1
DOIs
StatePublished - Aug 1997

Fingerprint

Monosomy
Chromosomes, Human, Pair 8
Chondrosarcoma
Chromosome Aberrations
Chromosomes, Human, Pair 12
Chromosomes, Human, Pair 4
Cytogenetics
Genes

ASJC Scopus subject areas

  • Cancer Research
  • Genetics
  • Molecular Biology

Cite this

Clonal chromosome aberrations with monosomy of chromosome 8 in a case of grade III chondrosarcoma. / Ptaszynski, Konrad; Ramesh, K.h.; Cannizzaro, Linda A.

In: Cancer Genetics and Cytogenetics, Vol. 97, No. 1, 08.1997, p. 60-63.

Research output: Contribution to journalArticle

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